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Contraception clinical trials at University of California Health

17 in progress, 6 open to eligible people

Showing trials for
  • PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception

    open to eligible females ages 18-40

    This is a Phase I multicenter, open-label, dose-ranging, three-dose PK and PD study of injectable LB administered as an IM or SQ injection at 40 mg, and subsequently at 50mg SQ and then 60 mg SQ depending on the preliminary pharmacokinetic and pharmacodynamic results obtained with 40 mg dosing.

    at UC Davis

  • Contraceptive Efficacy Study of Ovaprene

    open to eligible females ages 18-40

    This will be a multi-center, single arm, open-label study of Ovaprene, a non-hormonal intravaginal ring, to investigate the contraceptive effectiveness, safety and acceptability of Ovaprene.

    at UC Davis UCSF

  • Injectable DMAU for Male Contraception in Healthy Male Volunteers (CCN015)

    open to eligible males ages 18-50

    This is a Phase I multicenter, double-blind, single dose, dose-ranging study, in healthy men to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics of Dimethandrolone Undecanoate (DMAU) administered as an intramuscular or subcutaneous injection.

    at UCLA

  • Patient-centered Information on Permanent Contraception

    open to eligible females ages 21-45

    The goal of this study is to understand whether providing information to women with a strong desire to avoid future pregnancy about how tubal sterilization compares to long-acting reversible contraceptives improves perceived access to available contraceptives. Participants will: - Complete a baseline survey - Receive access to web-based educational resources - Complete a brief follow up survey immediately after exploring these web-based resources - Complete a follow-up survey 3 months after enrolling The investigators will compare outcomes among participants provided with access to a new website (intervention) summarizing recent patient-centered outcomes research (PCOR) comparing interval laparoscopic tubal sterilization and long-acting reversible contraception (LARC) to control participants provided with access to the existing Planned Parenthood website on tubal sterilization.

    at UCSF

  • FemBloc Permanent Birth Control

    open to eligible females ages 21-50

    Prospective, multi-center, international, unblinded, single-arm trial of subjects undergoing FemBloc followed by ultrasound confirmation test.

    at UC Davis

  • Progestin-only Contraception on Bleeding Patterns in Individuals Initiating GATT

    open to eligible people ages 18-50

    Gender diverse individuals who use gender-affirming testosterone therapy (GATT) to reduce gender dysphoria may also use progestins for contraception and to manage or suppress uterine bleeding. Research is limited, however, regarding expected bleeding patterns for individuals who choose to initiate GATT concurrently with a progestin. Clinicians who prescribe GATT do not have sufficient data to adequately counsel patients on side effects of concurrent progestin use and therefore extrapolate from studies conducted in cisgender women. This study is a prospective cohort study evaluating bleeding patterns and satisfaction among patients initiating GATT with or without concurrent initiation of a progestin contraceptive. The results from this study will enable clinicians to more accurately counsel patients using GATT on how the use of a progestin might affect their bleeding and whether this differs by progestin method.

    at UCSD

  • Tolerability of LevoCept

    Sorry, not yet accepting patients

    To assess the contraceptive efficacy (prevention of pregnancy) of LevoCept

    at UC Davis

  • Intervening on Women's Health for Rural Young Breast Cancer Survivors

    Sorry, not currently recruiting here

    The purpose of this study is to evaluate the effectiveness of a multi-component intervention to improve young breast cancer survivors' engagement in goal-concordant oncofertility care, concurrently with observing and gathering information on how the intervention is implemented. The investigators hypothesize that implementation of the intervention will result in increased young breast cancer survivors' engagement in goal-concordant oncofertility care.

    at UCSD

  • Intervening on Women's Health for Rural Young Cancer Survivors

    Sorry, not currently recruiting here

    The purpose of this pilot study is to evaluate the feasibility of a multi-component intervention to improve young female cancer survivors' engagement in goal-concordant reproductive health care. The investigators hypothesize that implementation of the intervention will result in increased young cancer survivors' engagement in goal-concordant reproductive health care.

    at UCSD

  • Contraceptive Efficacy and Safety of Etonogestrel (ENG) Implant Beyond 3 Years of Use (MK-8415-060)

    “We're looking for women who have been using Nexplanon for 2-1/2 to 3 years and want to continuing using the implant for a total of 5 years”

    Sorry, in progress, not accepting new patients

    The primary purpose of this study is to assess the efficacy and safety of the etonogestrel (ENG) contraceptive implant during participants' fourth and fifth years of use when used as the only method of contraception. The ENG implant is currently approved for a 3-year duration, and this study aims to confirm available evidence suggesting that the ENG implant remains highly effective when used up to 5 years.

    at UC Davis UCLA

  • Patient-Centered Reproductive Decision Support Tool for Women Veterans

    Sorry, in progress, not accepting new patients

    The investigators have developed a web-based decision support tool to help women Veterans get the information and care they need to achieve their reproductive goals, whether that includes optimizing their health before desired pregnancies or birth control to avoid unwanted pregnancies. The study will test the effect of sending a weblink to the decision tool to women Veterans prior to primary care visits at the VA. Half of participants will be sent a weblink before their appointment, and half will not be sent the link. The investigators hypothesize that participants who are sent the link will be more likely to report patient-centered discussions of their reproductive needs at visits, feel confident in communicating with their health care providers, have accurate knowledge about reproductive health, and choose birth control methods that best fit their preferences and needs.

    at UCSD UCSF

  • Postpartum Integration of Vaccines and Contraception Trial

    Sorry, not currently recruiting here

    This study aims to examine how to implement a gender-transformative post-partum family planning program integrated into community-based infant vaccination services, and to evaluate preliminary effectiveness of this approach on postpartum contraceptive use in a low resource, rural setting.

    at UCSD

  • Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

    Sorry, in progress, not accepting new patients

    The long term objective is to develop a gel to be used as a male contraceptive.

    at UC Davis UCLA

  • Ulipristal Acetate (UPA) Used Daily as a Contraceptive

    Sorry, currently not accepting new patients, but might later

    This is a Phase IIb multicenter, open-label, non-comparative trial of continuous daily oral 10 mg of ulipristal acetate (UPA) to evaluate its contraceptive efficacy as the primary method of contraception.

    at UC Davis UCSF

  • Tipping Point: Using Social Network Theory to Accelerate Scale and Impact

    Sorry, in progress, not accepting new patients

    This study will assess the nature and impact of social norms and networks to promote FP (Family Planning) intervention effects among low parity, married adolescent and young women in the Maradi region of Niger. Research activities will be layered on top of the USAID-funded Kulawa FP program that seeks to change FP-related behaviors among young, low parity women at scale in Niger in a subset of implementing villages. Kulawa, implemented by Save the Children U.S. (SCUS) and funded by USAID (2020-2025), will include small-group discussion for young, low parity girls coupled with community dialogues to address individual, social, and health system constraints to FP use and influence social norms that govern FP use. UCSD will not provide any services or implement any interventions as part of this study.

    at UCSD

  • UCSF College Health Study on Contraceptive Training and Education at Community Colleges

    Sorry, in progress, not accepting new patients

    The purpose of this study is to measure whether a training and education intervention for clinic staff and young women aged 18-25 on contraceptive methods, including intrauterine devices (IUDs) and the implant, will result in greater contraceptive knowledge and access among students in community colleges.

    at UCSF

  • Keep Contraceptive Arm Long Acting-iMplant (CALM) and Carry On

    Sorry, in progress, not accepting new patients

    The investigators will conduct an observational study comparing the number of bleeding days before and after contraceptive implant (Nexplanon) replacement.

    at UCSD

Our lead scientists for Contraception research studies include .

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