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Contraception clinical trials at University of California Health

16 in progress, 8 open to eligible people

Showing trials for
  • "My Decision" Tubal Sterilization Decision Support Tool

    open to eligible females ages 21-45

    This study seeks to test a web-based decision support tool developed to enhance low-income women's ability to make informed decisions about tubal sterilization that align with their preferences, values and reproductive goals. Half of participants will receive usual care, while the other half will use the web-based decision aid plus usual care. The investigators hypothesize that compared to women who receive usual care alone, women randomized to the decision aid arm will have greater knowledge about sterilization and alternative options, lower decisional conflict, and will be more satisfied with their contraceptive decision at 3-month follow-up.

    at UCSF

  • A Study to Assess Contraceptive Efficacy and Safety of Etonogestrel (ENG) Implant Beyond 3 Years of Use (MK-8415-060)

    open to eligible females ages up to 35 years

    The primary purpose of this study is to assess the efficacy and safety of the etonogestrel (ENG) contraceptive implant during participants' fourth and fifth years of use when used as the only method of contraception. The ENG implant is currently approved for a 3-year duration, and this study aims to confirm available evidence suggesting that the ENG implant remains highly effective when used up to 5 years.

    at UC Davis UCLA

  • Injectable DMAU for Male Contraception in Healthy Male Volunteers (CCN015)

    open to eligible males ages 18-50

    This is a Phase I multicenter, double-blind, single dose, dose-ranging study, in healthy men to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics of Dimethandrolone Undecanoate (DMAU) administered as an intramuscular or subcutaneous injection.

    at UCLA

  • Join a research study of a potential new form of male birth control

    “Couples are invited to participate in this two year study.”

    open to eligible people ages 18-50

    The long term objective is to develop a gel to be used as a male contraceptive.

    at UC Davis UCLA

  • Join a study to help us develop a new long lasting birth control shot

    “We are looking for women already using birth control methods without hormones or who are not sexually active with a man”

    open to eligible females ages 18-40

    This is a Phase I multicenter, open-label, dose-ranging, two-dose PK and PD study of injectable LB at administered as a SQ or IM injection at 40 mg and subsequently at 80 mg SQ or IM depending on the pharmacokinetic and pharmacodynamic results obtained at 40 mg.

    at UC Davis

  • Progestin-Only Pill Use and Breastfeeding Study

    open to eligible females ages 18 years and up

    This study will assess the impact of early initiation (less than one week postpartum) and delayed initiation (4 weeks postpartum) of two types of progestin-only contraceptive pills (POPs) on maternal, breastmilk, and infant outcomes.

    at UCSD

  • Taking a birth control pill or planning to? Willing to use a birth control implant too?

    “Join a study that aims to improve how well your birth control works at preventing pregnancy!”

    open to eligible females ages 18 years and up

    Women currently using or starting a combined oral contraceptive (COC) will be offered study enrollment. Study subjects will have a Nexplanon placed and followed for approximately 12 months to evaluate if they continue the implant, the COC, or both, and to assess bleeding patterns and adverse events.

    at UC Davis

  • UCSF College Health Study on Contraceptive Training and Education at Community Colleges

    open to eligible females ages 18-25

    The purpose of this study is to measure whether a training and education intervention for clinic staff and young women aged 18-25 on contraceptive methods, including intrauterine devices (IUDs) and the implant, will result in greater contraceptive knowledge and access among students in community colleges.

    at UCSF

  • Assessment of Contraceptive Safety and Effectiveness in Cystic Fibrosis

    Sorry, not currently recruiting here

    The long-term goal is to study the safety and effectiveness of hormonal contraception for women with cystic fibrosis (CF) and contribute to national guidelines that the Cystic Fibrosis Foundation and the Centers for Disease Control and Prevention (CDC) provide to clinicians. The study objectives are to determine whether hormonal contraceptive methods improve overall pulmonary health, worsen CF-related disease or CF liver disease, or are effective against unwanted pregnancy with concomitant CF transmembrane conductance regulator (CFTR) modulator use. The hypothesis is that hormonal contraceptive methods are safe and do not worsen CF-related complications over time,improve FEV-1 when compared to non-hormonal users, and oral birth control methods with CFTR modulator use.

    at UCSD

  • Compare Two Copper IUDs: Mona Lisa NT Cu380 Mini and ParaGard

    Sorry, in progress, not accepting new patients

    This will be a multi-site, participant-blinded, randomized clinical trial. The investigators will randomize 1000 eligible participants in a 4:1 ratio to two different copper IUDs: 800 to Mona Lisa NT Cu380 Mini and 200 to ParaGard.

    at UC Davis UCSF

  • Early vs. Interval Postpartum IUD Insertion

    Sorry, in progress, not accepting new patients

    Intrauterine devices (IUDs) are historically placed at a six-week postpartum visit for women who desire intrauterine contraception after delivery. A two-week postpartum visit could be a convenient time for women to receive contraception, including IUDs. Offering women IUDs at two-weeks postpartum may decrease the risk of undesired pregnancy and rapid repeat pregnancy. This study will compare IUD insertion at two different times after delivery: two-weeks and six-weeks postpartum. This will allow researchers to assess whether the timing of IUD placement affects whether an IUD is expelled, or pushed out of it's ideal location.

    at UCSD

  • Evaluating Household Visits and Small Groups to Increase Contraception Use Among Married Adolescent Girls in Rural Niger

    Sorry, accepting new patients by invitation only

    This study entails a quasi-experimental, mixed-methods (i.e., complementary quantitative and qualitative) outcome evaluation to assess the efficacy of the Reaching Married Adolescents (RMA) Interventions developed and implemented by Pathfinder International to increase contraception use and contraception use intentions among married adolescent girls ages 13-19 in three rural districts of the Dosso region of Niger. Intervention models (gender-synchronized household visits and small groups) will be tested using a randomized 4-arm outcome evaluation design; Arm 1 will receive household visits, Arm 2 will receive small groups; Arm 3 will receive household visits plus small groups, and Arm 4 will serve as the control group and will not receive any intervention. The quantitative component will consist of collecting quantitative baseline, 16-months follow-up, and 27-months survey data from randomly selected married adolescent girls (n=1200) and their husbands (n=1200) who are participating in each Arm of the study. Qualitative elements will include ethnography at two time points and semi-structured in-depth interviews half way through intervention implementation. A costing and cost effectiveness analysis will also be conducted to evaluate which intervention provides the largest gain in the primary outcomes for each dollar spent.

    at UCSD

  • Evaluation of the Efficacy, Safety, and Tolerability of LevoCept

    Sorry, not yet accepting patients

    To assess the contraceptive efficacy (prevention of pregnancy) of LevoCept

    at UC Davis

  • Keep Contraceptive Arm Long Acting-iMplant (CALM) and Carry On

    Sorry, not yet accepting patients

    The investigators will conduct an observational study comparing the number of bleeding days before and after contraceptive implant replacement.

    at UCSD

  • Study of the Safety and Efficacy of Ulipristal Acetate (UPA) Used Daily as a Contraceptive

    Sorry, currently not accepting new patients, but might later

    This is a Phase IIb multicenter, open-label, non-comparative trial of continuous daily oral 10 mg of ulipristal acetate (UPA) to evaluate its contraceptive efficacy as the primary method of contraception.

    at UC Davis UCSF

  • The Share Health Study: Teen Social Connections and Health (Phase 2)

    Sorry, in progress, not accepting new patients

    The purpose of this study is to determine whether delivery of SpeakOut, a behavioral intervention to increase social communication about long-acting reversible contraceptive (LARC) methods among adolescents, is associated with increased contraceptive use among the social contacts of SpeakOut recipients. The investigators will conduct a cluster randomized controlled trial of SpeakOut with adolescent LARC users and their female peers. Over three years, SpeakOut will be implemented in eight partner clinics. IUD and implant users aged 15 to 19 will be recruited online and invited to enroll in the evaluation study as "primary" participants and receive either SpeakOut or a control intervention about alcohol use called PartyWise. The social contacts of primary participants will be asked to enroll in the study as "secondary" participants. The study's primary outcome will be the proportion of sexually-active secondary participants who are using any contraceptive method at 9-month follow-up.

    at UC Davis UCSF

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