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Kidney Stones clinical trials at University of California Health

9 in progress, 7 open to eligible people

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  • A Study of Ureteral Stent Placement After Ureteroscopy for Kidney Stones

    open to eligible people ages 18 years and up

    The rationale for this study is to determine if there is a difference in complications among patients undergoing ureteroscopy for renal stones who receive a stent compared to not receiving a stent postoperatively.

    at UC Davis UCLA UCSD

  • Antibiotic Prophylaxis With Routine Ureteral Stent Removal

    open to all eligible people

    This study will be a single-institutional randomized, single-blinded prospectively controlled clinical trial of a single dose of Ciprofloxicin 500mg antibiotic tablet as prophylaxis at the time of office flexible cystoscopy with ureteral stent removal. The control group will be no prophylaxis oral antibiotics.

    at UCSD

  • Asymptomatic Renal Calculi in Recurrent Urinary Tract Infections

    open to eligible people ages 18 years and up

    This study will assess patients who have recurrent urinary tract infections and kidney stones which are not blocking the kidney or causing other problems. Currently, we don't know if taking out these stones will improve recurrent urinary tract infections or not. Patients will make a decision with their surgeon about removing or monitoring their stone(s). Whether or not their infections continue with surgery or monitoring will be noted, and this information may help to inform future treatment decisions. The purpose of this study is to assess if treatment of these asymptomatic stones affects the rate of recurrent urinary tract infections.

    at UCSD

  • Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones

    open to eligible people ages 18 years and up

    Pain associated with renal stone disease is typically caused by an obstructing stone that obstructs the flow of urine, which results in renal collecting system dilatation. Non-obstructing renal calculi that do not cause renal collecting system dilatation are thought to be painless. The objective of this study is to prospectively determine if the removal of non-obstructing renal calculi can reduce or eliminate participant's pain and/or improve their quality of life.

    at UC Davis UCLA UCSD

  • MIP Versus PCNL for Kidney Stone Disease

    open to eligible people ages 18 years and up

    The decision to use standard percutaneous nephrolithotomy (PCNL) versus mini-percutaneous nephrolithotomy (MIP) has been a subject of much debate in the urological community. The investigators propose a randomized controlled trial to compare the operative outcomes and complications of mini-percutaneous nephrolithotomy (mini-PCNL) versus standard PCNL for renal stones. The results of this study will help guide the decision making regarding these two procedures in the US population and provide further insight into the utility and safety of these procedures. A cost analysis will be performed, and it is hypothesized that the reusable components of the Storz MIP set will result in lower costs of the mini-PCNL procedure compared to standard PCNL.

    at UCSD

  • Pediatric KIDney Stone (PKIDS) Care Improvement Network

    open to eligible people ages 8-21

    The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for these surgeries.

    at UCLA

  • Struvite Stones Antibiotic Study

    open to eligible people ages 19 years and up

    The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).

    at UCSD

  • Ambulatory Versus Inpatient Percutaneous Nephrolithotomy

    Sorry, not yet accepting patients

    The goal of the study is to determine if ambulatory tubeless PCNL is safe and effective compared to inpatient PCNL with a nephrostomy tube.

    at UCSF

  • Video Home Visits for Dietary Counselling

    Sorry, not yet accepting patients

    This pilot study aims to develop a protocol for home video informed dietary counseling with the goal of reducing overall sodium consumption among kidney stone formers. To accomplish this the investigators will: 1)Assess which data available on video visits are most informative to convey patient sodium consumption, and 2) Administer virtual home visits with informed dietary counseling in our intervention arm and compare this to standard dietary counseling looking specifically at the outcome of 24-hour urine sodium excretion results over time. This study will benefit dramatically from the rapid growth of telehealth medical visits as a consequence of the SARS-CoV-2 pandemic, with the ultimate goal to improve and adapt patient dietary counseling for the prevention of kidney stone disease in the new and evolving era of telehealth.

    at UCSF

Our lead scientists for Kidney Stones research studies include .

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