Laryngopharyngeal Reflux clinical trials at University of California Health
2 in progress, 1 open to eligible people
open to eligible people ages 18-99
This 12 week biomarker targeted double blind randomized controlled trial (RCT) will enroll subjects with salivary pepsin positive laryngopharyngeal reflux (LPR) to assess efficacy of the external upper esophageal sphincter (UES) compression device, also known as the Reflux Band. Subjects will be randomized to one of two arms: control or experimental. Following the 8 week intervention period subjects in both arms will continue in a 4 week unblinded period. The primary hypothesis is that a significantly higher proportion of subjects in the experimental arm will meet the primary endpoint for symptom response, compared to subjects in the control arm.
Sorry, accepting new patients by invitation only
A multi-center, multi-year registry of patients with gastroesophageal reflux disease (GERD) undergoing diagnostic evaluation and/or treatment of GERD and associated diseases and complications.
at UC Irvine
Our lead scientists for Laryngopharyngeal Reflux research studies include Rena Yadlapati, MD, MSHS.