Mindfulness clinical trials at University of California Health
6 in progress, 3 open to eligible people
Defining Stress REsilience And Mindfulness Effects in Rheumatoid Arthritis
open to eligible people ages 18 years and up
This clinical trial will test a mindfulness program in individuals with rheumatoid arthritis (RA). The main goals of this pilot study are to: - Assess patient satisfaction with a mindfulness course - Identify barriers to participation in, or completion of, a mindfulness course - Gather initial information to understand how a mindfulness course impacts RA symptoms Participants will: - Complete online questionnaires - Attend two in-person study visits, involving a brief joint exam and blood draw - Roughly half the participants will have the chance to participate in an 8-week online mindfulness course - Roughly half the participants will be invited to participate in an online focus group following completion of the mindfulness course Researchers will compare those in the mindfulness course with those receiving standard care in preparation for a larger future study to see how mindfulness impacts stress and inflammation in individuals with RA.
at UCSF
Mindfulness Approach for Reducing Anxiety and Gloom in Ocular Inflammatory Diseases
open to eligible people ages 18 years and up
The proposed study is a block-randomized, controlled trial to evaluate the effects of a digital meditation and mindfulness practice on mental health in patients with non-infectious uveitis.
at UCSF
Mindfulness Engaged Neurostimulation for Depression
open to eligible people ages 18-65
Repetitive Transcranial Magnetic stimulation (rTMS) is an FDA-approved therapy for treatment resistant depression (TRD) that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region. But studies of rTMS alone show remission rates of ~30%. Additionally, rTMS has not been shown to improve cognitive functioning that may be an independent factor predicting treatment success. This study will develop a novel multimodal treatment, which combines intermittent theta burst stimulation (iTBS) - a type of rTMS with digital mindfulness training to engage brain plasticity, enhance cognition and alleviate depression symptoms in individuals with TRD.
at UCSD
Jazz Music and Mindfulness for Chronic Pain
Sorry, not yet accepting patients
Chronic pain, including spinal pain and osteoarthritis, is the leading cause of years lived with disability world-wide and the costliest health condition in the U.S. today. Compounding these concerns, opioid analgesics remain the primary pharmacological treatment for chronic pain. An estimated 21-29% of chronic pain patients receiving long-term opioid therapy develop opioid misuse, and opioid misuse portends addiction and overdose. Clearly, chronic pain patients need better, non-addictive treatment options designed to reverse the downward spiral of chronic pain.
at UC Irvine
Mindfulness Based Pain Reduction
Sorry, in progress, not accepting new patients
This is a development study with clinical outcomes. The investigators aim to develop and test an 8-week MBPR (Mindfulness-Based Pain Reduction) program, which draws on intervention work and clinical experience in the investigative team to optimize a mindfulness-based intervention for individuals with chronic pain. The overall goal of this study is to ensure that the MBPR program has been carefully refined and manualized in an in-person setting before performing clinical trials comparing MBPR to MBSR (Mindfulness-Based Stress Reduction) to test whether it improves pain outcomes. This study includes a Pain Attention Task that separates insula activation during experimental heat application between different pain attention conditions.
at UCSF
Mindfulness Based Stress Reduction for Parkinson's Disease: A Longitudinal Study
Sorry, in progress, not accepting new patients
To investigate the efficacy of Mindfulness-based Stress Reduction (MBSR),to improve HRQoL, cognition, and mood, as well as to determine the longevity of the treatment response in individuals with Parkinson's disease (PD).
at UCSD
Our lead scientists for Mindfulness research studies include Sean D Young Dawn M. Schiehser, PhD Nisha Acharya, MD, MS Jyoti Mishra, PhD Wolf E Mehling, MD.
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