Primary Sclerosing Cholangitis clinical trials at UC Health
4 in progress, 2 open to eligible people
A Study of Experimental Sulfasalazine for Primary Sclerosing Cholangitis (inflammation and scarring of the bile ducts)
“This research study hopes to find out if experimental treatment with sulfasalazine can help people with PSC.”
open to eligible people ages 15-80
This is a multicenter, randomized, double-blinded placebo controlled trial to assess the benefit of sulfasalazine in the treatment of PSC. The specific objectives of this study are to determine if sulfasalazine treatment 1) results in reduced serum ALP and other biomarkers of liver injury in PSC; 2) improves PSC patient symptoms; and 3) is safe in patients with PSC.
at UC Davis
A Study of the Safety and Effectiveness of Experimental Cilofexor for Primary Sclerosing Cholangitis (scarring of bile ducts)
open to eligible people ages 18-75
The primary objective of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing cholangitis (PSC).
at UC Davis UCSF
Sorry, not currently recruiting here
To demonstrate the clinical utility of the addition of per oral cholangioscopy (POCS) to standard endoscopic retrograde cholangiopancreatography (ERCP) with brushing cytology for diagnosis and early detection of cholangiocarcinoma in patients diagnosed with primary sclerosing cholangitis (PSC).
at UC Davis
Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Sclerosing Cholangitis Without Cirrhosis
Sorry, in progress, not accepting new patients
The primary objective of this study is to evaluate the safety and tolerability of Cilofexor in adults with primary sclerosing cholangitis (PSC).