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Respiratory Distress Syndrome clinical trials at UC Health
3 in progress, 1 open to new patients

  • Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome

    “The study team wants to know if adding a sigh-type of breath to a ventilator reduces chances of developing more serious lung problems.”

    open to eligible people ages 18-89

    A randomized, concurrent controlled trial to assess if adding sigh breaths to usual invasive mechanical ventilation of victims of trauma who are at risk of developing ARDS will decrease the number of days they require invasive mechanical ventilation.

    at UCSF

  • Study of early treatment, high dose Vitamin D impact on improving outcomes of ICU patients

    “Does Vitamin D improve a patient’s chances of living through a severe illness?”

    Sorry, in progress, not accepting new patients

    This study aims to evaluate the effect of early administration of high-dose vitamin D3 in reducing all-cause, all-location mortality in vitamin D deficient patients at high risk for ARDS. Patients will be screened for vitamin D deficiency (<20 ng/mL). Only patients screened as vitamin D deficient will be randomized. Half of the vitamin-D deficient patients will be given a high-dose of vitamin D3 and the other half will be given a placebo.

    at UCSF UCLA UC Davis

  • Study of Higher breathing machine pressure settings with/without muscle relaxant for Acute Respiratory Distress Syndrome (ARDS)

    “Does early treatment with muscle relaxant improve recovery from lung injury?”

    Sorry, in progress, not accepting new patients

    This study evaluates whether giving a neuromuscular blocker (skeletal muscle relaxant) to a patient with acute respiratory distress syndrome will improve survival. Half of the patients will receive a neuromuscular blocker for two days and in the other half the use of neuromuscular blockers will be discouraged .

    at UCSF UCLA UC Davis