Sonodynamic Therapy clinical trials at University of California Health

2 research studies open to eligible people

Showing trials for

  • Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients With DIPG

    open to eligible people ages 5 years and up

    The primary objectives of this trial are to evaluate the safety and tolerability of sonodynamic therapy (SDT) using SONALA-001 and Exablate Type 2.0 device and to determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D) of MR-Guided Focused Ultrasound (MRgFUS) energy in combination with SONALA-001 in subjects with diffuse intrinsic pontine glioma Funding Source - FDA OOPD

    at UCSF

  • Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2 in Subjects With Progressive or Recurrent GBM

    open to eligible people ages 18 years and up

    The primary objectives of this trial are to evaluate the safety, dose-limiting toxicities, maximum tolerated dose (MTD), maximum administered dose (MAD) and recommended Phase 2 dose (RP2D) for future study after a single treatment of SONALA-001 in combination with MRgFUS and to evaluate preliminary efficacy of sonodynamic therapy (SDT) using SONALA-001 and Exablate Type 2.0 device in subjects with progressive or recurrent GBM.

    at UCSF

Our lead scientists for Sonodynamic Therapy research studies include .

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