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Stress clinical trials at UC Health
4 in progress, 2 open to new patients

  • Enhanced Stress Resilience Training for Residents

    open to eligible people ages 18-64

    Burnout and overwhelming stress are growing issues in medicine and are associated with mental illness, performance deficits and diminished patient care. Among surgical trainees, high dispositional mindfulness decreases these risks by 75% or more, and formal mindfulness training has been shown feasible and acceptable. In other high-stress populations formal mindfulness training has improved well-being, stress, cognition and performance, yet the ability of such training to mitigate stress and burnout across medical specialties, or to affect improvements in the cognition and performance of physicians, remains unknown. To address these gaps and thereby promote the wider adoption of contemplative practices within medical training, investigators have developed Enhanced Stress Resilience Training, a modified form of MBSR - streamlined, tailored and contextualized for physicians and trainees. Investigators propose to test Enhanced Stress Resilience Training (ESRT), versus active control and residency-as-usual, in mixed-specialty interns (from Emergency Medicine, Internal Medicine, Pediatrics, Family Practice, OBGYN and Surgery Departments) evaluated for well-being, cognition and performance changes at baseline, post-intervention and three or six-month follow-up.

    at UCSF

  • Ethnic Influences on Stress, Energy Balance and Obesity in Adolescents

    open to eligible females ages 13-17

    The study will examine the mechanisms linking race, stress and biobehavioral factors to energy balance and obesity in both natural and controlled environments in African-American and Caucasian adolescent females.

    at UC Irvine

  • Life Enhancing Activities for Family Caregivers

    Sorry, in progress, not accepting new patients

    Life Enhancing Activities for Family Caregivers is a six-week program designed to increase positive affect in people who care for a family member with dementia. The intervention consists of 6 weekly one-hour sessions conducted one-on-one with a trained facilitator to teach simple skills that are practiced at home in a study-supplied workbook. The program is preceded and followed by a 30-45 minute questionnaire. Follow-up assessments will be conducted at 1-month, 3-months, and 6-months post intervention. Primary hypothesis is that experimental subjects who participate in LEAF will demonstrate significantly greater improvements in psychological outcomes and will engage in more problem focused and positive appraisal forms of coping compared to the wait-list control condition.

    at UCSF

  • The Impact of 8 Weeks of a Digital Meditation Application on Work Stress

    Sorry, not yet accepting patients

    The aim of this study is to test the effects of a digital meditation intervention in a sample UCI employees who report mild to moderate stress. We will randomize UCI employees to either 8-weeks of a digital meditation intervention (using the commercially available application Headspace) or a waitlist control condition.

    at UC Irvine UCSF

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