Tobacco clinical trials at University of California Health

23 in progress, 13 open to eligible people

Showing trials for

  • Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder

    open to eligible people ages 22 years and up

    The proposed project will include enrollment of 200 daily tobacco cigarette users, ages 22+, from the San Diego community. Participants will be assessed on the VR Nicotine Cue Exposure paradigm then randomized (stratified on age and sex) to receive…

    at UCSD

  • Cannabidiol for Reducing Cigarette Use

    open to eligible people ages 18-65

    The goal of this research is to evaluate the efficacy of cannabidiol (CBD) in reducing cigarette smoking. Although there are safe and effective treatments for smoking cessation, not everyone who attempts smoking cessation is successful, even with…

    at UCLA

  • Pharmacodynamics of Synthetic Nicotine

    open to eligible people ages 21-65

    In a crossover study, experienced electronic cigarette users will vape 3 different forms of nicotine: natural (derived from tobacco), synthetic, or a 50:50 mixture of both natural and synthetic. The investigators will compare nicotine metabolism,…

    at UCSF

  • Contingency Management for Veteran Smokers Undergoing Major Elective Surgery

    open to eligible people ages 18 years and up

    The goal of this study is to design and test the first mobile contingency management (CM) smoking cessation intervention for military Veterans undergoing major elective surgery. Smoking is the leading risk factor for postoperative complications and…

    at UCSF

  • Cytisinicline on Neural Substrates of Cigarette Cue-reactivity

    open to eligible people ages 18-65

    This study will randomize 64 non-treatment seeking individuals who smoke cigarettes daily in a double-blind, placebo-controlled laboratory study testing the effects of cytisinicline on the neural substrates of cigarette cue reactivity.

    at UCLA

  • Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

    open to eligible people ages 45-80

    This clinical trial evaluates the usefulness of using a smartphone-based HIV-specific smoking cessation intervention at the time of lung cancer screening in helping people living with HIV quit smoking. Positively Smoke Free - Mobile may help…

    at UCSD

  • Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation

    open to eligible females ages 18 years and up

    This develops a novel behavioral tobacco cessation program for pregnant smokers in San Bernardino County.

    at UCSF

  • PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

    open to eligible people ages 18 years and up

    This is a research study about a smoking cessation program tailored for adults with serious mental illness (SMI). The program uses a Videogame-based Physical (VIP) activity, smoking cessation counseling, and medication (bupropion),

    at UCSF

  • Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC)

    open to eligible people ages 21-70

    This is a crossover study that will examine use behaviors, chemical exposures, and biological effects of Standardized Research Electronic Cigarette (SREC) compared to usual brand e-cigarette use in natural or synthetic nicotine users.

    at UCSF

  • Secondhand Tobacco Smoke and Cardiovascular Disease

    open to eligible people ages 40 years and up

    This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic Obstructive Pulmonary …

    at UCSF

  • Smoke-free Home Study in Subsidized Housing

    open to eligible people ages 18 years and up

    Comprehensive smoke-free policies have the potential to substantially reduce tobacco-related disparities among populations in subsidized housing. This study fills this gap by identifying approaches to increase the implementation of smoke-free…

    at UCSF

  • Smoking Cessation CM for Veterans With or at Risk for Cancer

    open to eligible people ages 18 years and up

    Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping Veterans quit smoking…

    at UCSF

  • Tobacco Cessation Care for Cancer Patients by Automated Interactive Outreach

    open to eligible people ages 18 years and up

    This is a multi-arm, randomized controlled, pilot study which will recruit cancer patients who have been seen by a UCSF Cancer Center-affiliated clinical department to evaluate the efficacy of "CareConnect". This is the first study to assess the…

    at UCSF

  • Tobacco, E-Cigarette, and Cannabis Waste

    Sorry, in progress, not accepting new patients

    This study tests of effect of brief education and support about tobacco, e-cigarette, and cannabis waste (TECW) on knowledge, beliefs, behavior, and TECW on two college campuses.

    at UC Davis

  • Chatbot for Online Support Groups to Treat Tobacco Addiction

    Sorry, not yet accepting patients

    Investigators will conduct a pilot RCT to test the efficacy of an intelligent chatbot to aid small, private, quit-smoking peer support groups. Participants will be randomized to an intervention arm (chatbot-enhanced support group), or a control arm…

    at UC Irvine

  • Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study

    Sorry, not yet accepting patients

    The goal of this clinical trial is to determine whether Emotional Brain Training (EBT), a behavioral modification method, can help manage stress and health problems related to addiction. EBT teaches skills to deactivate harmful circuits (automatic…

    at UCSF

  • Enhanced Multicomponent Proactive Navigator-Assisted Cessation of Tobacco Use in Low-Income Patients

    Sorry, not currently recruiting here

    This research study is being conducted to test the effectiveness of the Enhanced Multicomponent Proactive Navigator-Assisted Cessation of Tobacco Use (EMPACT-Us), an innovative suite of tobacco cessation services designed in partnership with…

    at UCSD

  • Financial Incentives for Smoking Treatment II

    Sorry, accepting new patients by invitation only

    Financial incentives for motivating changes in health behavior, particularly for smoking and other morbid habits, are increasingly being tested by health insurers, employers, and government agencies. However, in using incentive programs for smoking…

    at UCLA

  • Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures

    Sorry, not yet accepting patients

    This is an unblinded pilot study of an environmental exposure to secondhand cannabis smoke in one group of healthy nonsmokers.

    at UCSF

  • N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use

    Sorry, in progress, not accepting new patients

    Tobacco and cannabis co-use is a common and growing public health problem, especially in states that have legalized cannabis. There are no pharmacologic treatments for co-occurring tobacco and cannabis use. Co-use may make quitting either substance…

    at UCSF

  • Secondhand Smoke Respiratory Health Study

    Sorry, in progress, not accepting new patients

    Exposure to secondhand tobacco smoke (SHS) is associated with diverse health effects in nonsmokers. Flight attendants (FA) who worked on commercial aircraft before the ban on tobacco smoking (exposed FAs) had high, long-term levels of occupational…

    at UCSF

  • Clinical Pharmacology of Marijuana-Tobacco Co-administration

    Sorry, not yet accepting patients

    This is a crossover, randomized, double-blinded clinical pharmacology study enrolling dual cannabis-tobacco smokers to better understand the combined effects of co-administering cannabis and tobacco. The project aims to describe the pharmacokinetics …

    at UCSF

  • Varenicline for Smoking Reduction in Veterans Not Ready To Quit

    Sorry, not yet accepting patients

    In order to reduce the prevalence of cigarette smoking among Veterans, it is vital that the investigators offer effective tobacco treatment to all Veterans who smoke, including those not ready to make a quit attempt. Smoking treatments currently…

    at UCSD

Our lead scientists for Tobacco research studies include .

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