for females (full criteria)
Healthy Volunteers
healthy people welcome
study started
estimated completion
Principal Investigator
Andrea Z LaCroix, PhD (ucsd)
Photo of Andrea Z LaCroix
Andrea Z LaCroix



The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent. It includes the National Institute of Aging (NIA) Go4Life® Exercise & Physical Activity materials 3 and WHISH developed targeted materials based on Go4Life® to provide inspirational tips and recommendations about how to achieve nationally recommended levels of PA and overcome barriers to exercise, with a means for self-monitoring and setting personal goals. The intervention builds upon evidence-based behavioral science principles and intervention components that have proven to be effective in increasing PA in older women, with innovative adaptive approaches to tailoring the delivery to meet individual (personal) needs.


Myocardial Infarction Stroke Cardiovascular Mortality Hip Fractures Falls Mortality Venous Thromboembolic Event Peripheral Artery Disease Physical Function Coronary Revascularization Mobility and Independence Clinical (Non-hip) Fractures Physical Activity National Institute of Aging Go4Life Postmenopausal Women Balance Strength Exercise Cardiovascular Disease Coronary Artery Bypass Graft (CABG) Percutaneous Coronary Intervention (PCI) Peripheral Arterial Disease Thromboembolism Infarction Fractures, Bone


You can join if…

Open to females

  • Currently enrolled in the Women's Health Initiative (WHI) Extension Study
  • Known to be alive
  • Cardiovascular outcomes will be available (enrolled in the WHI Medical Records Cohort or linked to Medicare Data)

You CAN'T join if...

  • Inability to walk
  • Dementia
  • Residing in a nursing home

Lead Scientist at UC Health

  • Andrea Z LaCroix, PhD (ucsd)
    Dr. LaCroix received her PhD in Epidemiology from the University of North Carolina at Chapel Hill and completed a postdoctoral fellowship in cardiovascular disease at The Johns Hopkins University.


in progress, not accepting new patients
Start Date
Completion Date
Fred Hutchinson Cancer Research Center
Study Type
Last Updated