Impact of Sinus Surgery on Individuals With Cystic Fibrosis

a study on Chronic Rhinosinusitis Cystic Fibrosis Fibrosis

Summary

Eligibility
for people ages 18-99 (full criteria)
Location
at UCLA
Dates
study started
completion around
Principal Investigator
by Daniel M. Beswick, MD (ucla)
Headshot of Daniel M. Beswick
Daniel M. Beswick

Description

Summary

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.

Official Title

The Impact of Sinus Surgery in the Era of Highly Effective Modulatory Therapy

Keywords

Chronic Rhinosinusitis (Diagnosis), Cystic Fibrosis, Chronic Rhinosinusitis, Endoscopic Sinus Surgery, Rhinosinusitis, Fibrosis

Eligibility

You can join if…

Open to people ages 18-99

  1. Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old).
  2. Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride
  3. Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines
  4. chronic rhinosinusitis symptoms persisting beyond initial medical treatment
  5. Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment

You CAN'T join if...

  1. Underwent endoscopic sinus surgery in past 12 months
  2. Will obtain follow up care at non-participating institutions
  3. Unable to complete follow-up surveys

Locations

  • University of California, Los Angeles accepting new patients
    Los Angeles California 90095 United States
  • Stanford University accepting new patients
    Stanford California 94305 United States

Lead Scientist at University of California Health

  • Daniel M. Beswick, MD (ucla)
    Associate Professor-in-Residence, Head and Neck Surgery, Medicine. Authored (or co-authored) 99 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Los Angeles
ID
NCT04469439
Study Type
Observational
Participants
Expecting 170 study participants
Last Updated