Heart Attack clinical trials at University of California Health
13 in progress, 3 open to eligible people
ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
open to eligible people ages 18 years and up
The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes.…
at UC Irvine UCLA UCSD
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
open to eligible people ages 18 years and up
Cardiac rehabilitation is a medically recommended program for patients with certain heart conditions. It includes exercise training, health education, and counseling. Unfortunately, many patients do not participate in cardiac rehabilitation. Some…
at UCSF
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease
open to eligible people ages 18 years and up
COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment elevation myocardial…
at UCLA
Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke
Sorry, in progress, not accepting new patients
This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.
at UCLA
Evaluation in STEMI Patients Using FDY-5301
Sorry, in progress, not accepting new patients
To assess the effect of FDY-5301 on cardiovascular mortality and acute heart failure events in subjects with an anterior STEMI undergoing pPCI.
at UCLA
Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
Sorry, in progress, not accepting new patients
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).
at UCLA UCSD UCSF
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
Sorry, in progress, not accepting new patients
The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipid management alone when administered in the acute setting to reduce myocardial infarction, ischemic…
at UC Irvine UCLA
IRI-EXPLORE: A Study to Test Whether BI 765845 Helps People Who Have Had a Heart Attack
Sorry, not currently recruiting here
This study is open to adults aged 18 and over who have just had a heart attack. The purpose of this study is to find out whether a medicine called BI 765845 helps people who have had a heart attack. The investigators also want to test how well…
at UCLA
Reducing Blood Pressure in Patients With High Cardiovascular Risk in the Safety-Net
Sorry, not currently recruiting here
BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services public healthcare system. The goal of this clinical …
at UC Irvine UCLA
Selatogrel Outcome Study in Suspected Acute Myocardial Infarction
Sorry, accepting new patients by invitation only
This study will randomize patients recently discharged from the hospital with a confirmed diagnosis of type 1 acute myocardial infarction (Thygesen et al. 2018) and having additional cardiovascular risk factors.
at UCLA
Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock
Sorry, accepting new patients by invitation only
The CERAMICS study is designed to more clearly delineate the current care of acute myocardial infarction with cardiogenic shock (AMICS) patients who are treated with mechanical circulatory support (MCS) devices in the United States with significant…
at UCLA
Heart Attack Research Program- Imaging Study
Sorry, not currently recruiting here
The HARP study is a multi-center, diagnostic observational study employing standardized imaging protocols in patients with MINOCA (MI with Non Obstructive Coronary Arteries) to determine the underlying diagnosis in each participant. Participants…
at UCSD
Vascular Events In Surgery patIents cOhort evaluatioN - Cardiac Surgery
Sorry, in progress, not accepting new patients
Worldwide over 2 million adults (>30,000 Canadians) undergo heart surgery annually. Although heart surgery provides important survival benefits, it is associated with potential major complications such as death, stroke, and heart attack. There is…
at UCLA
Our lead scientists for Heart Attack research studies include Rushi Parikh, MD Alexis Beatty, MD, MAS Alejandra Casillas, MD Eric H. Yang, MD.
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