Overactive Bladder clinical trials at University of California Health

8 in progress, 6 open to eligible people

Showing trials for

  • Practice-Based Intervention to Improve Care for a Diverse Population of Women with Urinary Incontinence

    open to eligible people ages 18 years and up

    The main goal of this clinical trial is to improve the care for urinary incontinence (UI) provided to adult women by primary care providers. The main questions it aims to answer are: - Can a practice-based intervention involving primary care providers lead to improved quality of incontinence care? - Will this intervention reduce the utilization of specialist care for urinary incontinence? - What effect will this intervention have on patient outcomes, including disease-specific outcomes, symptom severity, quality of life, and patient knowledge? - Does our intervention reduce disparities in care? Provider participants will be randomized at the office level to either an intervention group or a delayed intervention (control) group. The intervention group will receive an intervention consisting of academic detailing, clinical decision support tools, electronic referral, and the ability to refer to an advanced practice provider for co-management. The delayed intervention group will provide usual care until the crossover phase of the study, at which point they will receive the same intervention as the intervention group. Patient participants will bring up urinary incontinence with their primary care provider and complete three electronic surveys. Researchers will compare the intervention group to the delayed intervention (control) group to see if the intervention results in increased adherence to evidence-based quality indicators.

    at UCLA UCSD

  • Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

    open to eligible people ages 18 years and up

    A prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the eCoin® implanted tibial nerve stimulator in subjects with urgency urinary incontinence (UUI).

    at UC Irvine

  • Oxybutynin for Post-surgical Bladder Pain and Urgency

    open to eligible people ages 4-8

    Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

    at UC Davis

  • CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology

    open to eligible people ages 18 years and up

    This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim® system. Subjects from both groups will immediately start with therapy. The primary endpoint is a ≥ 50% reduction in number of incontinence episodes associated with urgency at the 3-month visit, with additional measurements assessed at 14 days, 1, 6, 9 and 12-months.

    at UC Irvine

  • TReating Incontinence for Underlying Mental and Physical Health

    open to eligible females ages 60 years and up

    The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy and b) no bladder pharmacotherapy on cognitive, urinary, and other aging-related functional outcomes in ambulatory older women with urgency-predominant urinary incontinence and either normal or mildly impaired cognitive function at baseline.

    at UCSF

  • Reliability of Urodynamics SysTem

    open to eligible females ages 18 years and up

    The goal of this prospective trial is to assess the safety and reliability of the Glean Urodynamics System (GUS) in adult females with lower urinary tract symptoms. The main question[s] it aims to answer are: • What is GUS's ability to safely and reliably conduct wireless, catheter-free monitoring of vesical pressure compared to the vesical pressures collected with conventional urodynamics? Participants will undergo a conventional urodynamics exam, a simultaneous urodynamics exam with GUS, ambulatory urodynamics with GUS, and extended home monitoring with GUS. Researchers will compare GUS data with that from a conventional urodynamics exam.

    at UCSD

  • BlueWind RENOVA iStim™ System for the Treatment of OAB

    Sorry, not currently recruiting here

    The OASIS study is prospective, interventional, multi-center study to evaluate the safety and efficacy of the BlueWind RENOVA iStim™ implantable tibial neuromodulation System for the treatment of patients diagnosed with overactive bladder.

    at UC Irvine

  • Wearables for the Bladder: an In-home Treatment Feasibility Pilot Study

    Sorry, in progress, not accepting new patients

    The goal is to investigate the feasibility and effects of adding "wearables for the bladder" devices to conventional pelvic floor physical therapy (PFPT) to bladder function, in people with multiple sclerosis (MS).

    at UCSF

Our lead scientists for Overactive Bladder research studies include .

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