for people ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
study started
completion around
Principal Investigator
by Peggy Reynolds, PhD (ucsf)



The DREAM Cohort is a longitudinal observational study developed to enhance our understanding of how multiple exposures to environmental chemicals and pollutants across a diverse population of pregnant women and their offspring are linked to cancer risks. Because pregnancy induces multiple maternal hormonal and physiological changes that can increase cancer susceptibility to environmental chemical exposures, this study will focus on pregnancy as a period of particular vulnerability to toxic agents.

Official Title

DREAM: Discovering Cancer Risks From Environmental Contaminants And Maternal/Child Health


The environmental exposures will focus on two major components: Consumer product related chemicals (including per- and polyfluoroalkyl substances (PFAS), phthalates and plasticizers, phenolic compounds, pesticides, and aromatic amines) measured via biomonitoring and prioritized based on widespread public exposure; and environmental pollutants in air and water, evaluated via geographic information system analyses of participants' residential histories.

The study team will collect questionnaire data and biospecimen samples starting at the second trimester of pregnancy up until the child reaches four years of age. A Cohort Ambassador Program will also be established to invite participants across our three sites to provide continuous feedback which will be integrated into the research priorities.


Cancer, Cancer Risk, Environmental Cancer Risk, Maternal-Child Cancer Risk, Environmental Contaminants


You can join if…

Open to people ages 18 years and up

  • Pregnant women, over the age of 18 years.
  • English or Spanish-speaking.
  • Children born of participants enrolled during pregnancy will be enrolled in the DREAM cohort.
  • Inclusion criterion for the DREAM Cohort Ambassador Program is limited to research participants in the DREAM Cohort.

You CAN'T join if...

  • Women under the age of 18.
  • Women expecting the birth of multiples (twins, triplets, etc.).


  • Fresno Community Regional Medical Center accepting new patients
    Fresno California 93721 United States
  • University of California, San Francisco accepting new patients
    San Francisco California 94143 United States
  • University of California, Berkeley accepting new patients
    Berkeley California 94720 United States

Lead Scientist at University of California Health

  • Peggy Reynolds, PhD (ucsf)
    Dr. Peggy Reynolds is an epidemiologist with research interests focused on environmental risk factors for cancer. Her research program has incorporated geographic information system tools and studies of biomarkers of exposure and effect to assess risk relationships for children and adults.


accepting new patients
Start Date
Completion Date
University of California, San Francisco
Study Type
Expecting 10000 study participants
Last Updated