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Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture

a study on Fibromyalgia

Summary

Eligibility
for people ages 18-80 (full criteria)
Location
at UC Irvine
Dates
study started
completion around
Principal Investigator
by Ariana Nelson, MD (uci)

Description

Summary

This study aims to see whether acupuncture can help fibromyalgia patients by giving them acupuncture treatment and seeing whether acupuncture helps enhance the effects of an opioid.

Details

The investigator hypothesizes that traditional acupuncture (TA) enhances binding of the MOR receptor which will then enhance the pain-reducing effects of opioids compared to sham acupuncture (SA). The investigator will test the hypothesis by giving participants a validated Brief Pain Inventory to complete during the pre-therapy opioid challenge and one week after TA or SA therapy is completed.

Keywords

Fibromyalgia, Acupunture, Myofascial Pain Syndromes, Traditional acupuncture

Eligibility

You can join if…

Open to people ages 18-80

  • Are 18 - 80 years old
  • have been diagnosed with Fibromyalgia for more than 6 months

  • Are already using chronic, continuous opioid therapy, including but not limited to the use of Hydrocodone (Norco), Oxycodone (Percocet), morphine, methadone or Tylenol

    3 daily

  • Have moderate to excruciating pain at baseline, determined by a 5 or greater score on the Visual Analogue Scale (VAS)

You CAN'T join if...

  • Are younger than 18 or older than 80 years old
  • Have been diagnosed with a Substance Use Disorder (SUD)
  • Pregnant
  • Have an active litigation or worker's compensation case
  • Have an active mental health diagnosis, such as bipolar disorder, psychosis, or suicidal ideation
  • Are prescribed and actively using low dose Naltrexone . Have tried acupuncture in the last 6 months

Location

  • UCI Health Susan Samueli Integrative Health Institute
    Irvine California 92617 United States

Lead Scientist at University of California Health

  • Ariana Nelson, MD (uci)
    Associate Clinical Professor, Anesthesiology and Perioperative Care, School of Medicine. Authored (or co-authored) 36 research publications