Summary

Eligibility
for people ages 19-70 (full criteria)
Healthy Volunteers
healthy people welcome
Location
at UC Davis
Dates
study started
study ends around

Description

Summary

The goal of this study is to learn about the effects of eating kimchi on the gut health of healthy adults in the USA. The investigators will be researching the changes in the gut microbiome, biomarkers of gut health and cardiometabolic health after consuming fermented and unfermented cabbage.

The main questions it aims to answer are:

Does eating kimchi (fermented cabbage) result in enrichment of lactic acid bacteria in the stools of participants? Does eating kimchi result in metabolic changes in the gut microbiome, biomarkers of gut and cardiometabolic health of participants? Researchers will compare a group of participants eating fermented cabbage (kimchi) daily to a group of participants eating non-fermented cabbage daily.

Participants will:

Eat kimchi or cabbage daily for 3 weeks. Visit the study site for brief visits up to 5 times. Have blood drawn and provide a fecal sample 2 times - at beginning and end of the 3 week study.

Keep occasional records of food intake and questionnaires about any gastrointestinal symptoms that participants may have.

Official Title

Kimchi and Gut Health - Kimchi Effects on the Human Gut Microbiome

Keywords

Healthy Adult Participants, Healthy adult, GI health, Fermented food, 60 grams per day of intervention food, Kimchi, Cabbage

Eligibility

You can join if…

Open to people ages 19-70

  • BMI of 25-30 kg/m2
  • No or occasional consumption of kimchi (3 or fewer times per week)
  • Willing to eat study food every day for 3 weeks
  • Willing to participate in study protocols

You CAN'T join if...

  • Allergy to cabbage and /or cruciferous family vegetables
  • Allergy to kimchi ingredients such as shellfish and fish sauce
  • Daily consumption of kimchi
  • Diagnosed digestive issues such as irritable bowel syndrome (IBS) or gastrointestinal inflammatory bowel disease (IBD) or conditions such as Crohn's disease
  • Previous bowel surgery that disrupts the digestive flow, motility or gastric emptying process
  • Antibiotics used in the 2 months prior to enrollment
  • Unwillingness to discontinue probiotics during study and washout period
  • Active diagnosis and/or treatment for cancer

Location

  • Ragle Human Nutrition Center
    Davis California 95616 United States

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Davis
ID
NCT07435831
Study Type
Interventional
Participants
Expecting 60 study participants
Last Updated