Cannabis clinical trials at University of California Health

16 in progress, 10 open to eligible people

Showing trials for

  • Tobacco, E-Cigarette, and Cannabis Waste

    open to eligible people ages 18-25

    This study tests of effect of brief education and support about tobacco, e-cigarette, and cannabis waste (TECW) on knowledge, beliefs, behavior, and TECW on two college campuses.

    at UC Davis

  • Brain Mechanisms Supporting Cannabis-induced Pain Relief

    open to eligible people ages 21-65

    The American Academy of Pain Medicine has labeled pain as a "silent epidemic" due to its staggering costs to society (over $500 billion/year) and widespread prevalence (affects over 100 million Americans). Thus, it is imperative to test and validate …

    at UCSD

  • Cannabis Effects as a Function of Sex (CanSex)

    open to eligible people ages 21-55

    The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-related effects between men and women

    at UCLA

  • Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity

    open to eligible people ages 18 years and up

    This study will address whether cannabis affects antiretroviral therapy (ART) drug concentrations, mood, and thinking. The project will have two phases. Phase 1 is an observational study, in which 120 people will be assessed to evaluate the effects…

    at UCSD

  • Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

    open to eligible people ages 21-25

    The goal of this interventional study is to determine the impact of high potency THC product use on cognitive function of young adults aged 21-25. The main question it aims to answer is: will cannabis users who switch to less potent THC products…

    at UCSF

  • Cannabis Use, Cognition, and the Endocannabinoid System in HIV

    open to eligible people ages 18-65

    Understanding how co-morbidities in persons with HIV (PWH) such as substance use affect risk-taking, decision-making, and other cognitive behaviors is important given implications for everyday functioning and transmission risk. The high prevalence…

    at UCSD

  • Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV

    open to eligible people ages 21-70

    This study has the potential to contribute to a more complete understanding of the independent and combined effects of cannabis use and HIV on the brain and on inflammation. Such knowledge may inform future strategies for treating brain disease and…

    at UCSD

  • Cannabis Derivatives in Neuropathic Pain

    open to eligible people ages 21 years and up

    Chronic neuropathic pain (CNP) is disabling. Research on frontline treatments for CNP, shows inconsistent outcomes and dissatisfaction among Veterans. Veterans and clinicians have shown significant interest in cannabis derivatives (THC, CBD) for…

    at UCSD

  • Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome

    open to eligible people ages 21-75

    The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS). Multiple psychophysical approaches will be conducted in conjunction with psychological and…

    at UCSD

  • MARY-JANE Cannabis and Heart Rhythm Trial

    open to eligible people ages 21 years and up

    Despite recreational cannabis now being legal in 23 states, where more than 100 million Americans reside, studies on the actual health effects are limited. This study is a randomized trial, where each participant will be instructed to consume or…

    at UCSF

  • Inhaled Cannabis for Acute Migraine Treatment

    Sorry, currently not accepting new patients, but might later

    This pilot crossover study will evaluate 3 different potencies of inhaled cannabis (2.5%, 5%, and 10%) and inhaled placebo cannabis for the acute treatment of migraine.

    at UCSD

  • High Potency Cannabis: Acute and Protracted Effects

    Sorry, not yet accepting patients

    The purpose of this research is to assess the effects of smoked cananbis when cannabis is smoked during periods of cannabis use as usual and after a brief period of abstinence.

    at UCLA

  • Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures

    Sorry, not yet accepting patients

    This is an unblinded pilot study of an environmental exposure to secondhand cannabis smoke in one group of healthy nonsmokers.

    at UCSF

  • N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use

    Sorry, in progress, not accepting new patients

    Tobacco and cannabis co-use is a common and growing public health problem, especially in states that have legalized cannabis. There are no pharmacologic treatments for co-occurring tobacco and cannabis use. Co-use may make quitting either substance…

    at UCSF

  • TACUNA (Traditions and Connections for Urban Native Americans)

    Sorry, in progress, not accepting new patients

    This study responds to Request For Application-DA-19-035, HEAL (Helping End Addiction Long Term) initiative: Preventing OUD in Older Adolescents and Young Adults (ages 16-30) by developing and implementing a culturally centered intervention to…

    at UCLA

  • Clinical Pharmacology of Marijuana-Tobacco Co-administration

    Sorry, not yet accepting patients

    This is a crossover, randomized, double-blinded clinical pharmacology study enrolling dual cannabis-tobacco smokers to better understand the combined effects of co-administering cannabis and tobacco. The project aims to describe the pharmacokinetics …

    at UCSF

Our lead scientists for Cannabis research studies include .

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