Assessment Tool for Older Patients With Cancer
a study on Cognitive/Functional Effects Cancer, General Solid Tumor
Summary
- Eligibility
- for people ages 65-120 (full criteria)
- Location
- at UC Irvine
- Dates
- study startedestimated completion
Description
Summary
RATIONALE: A study that assesses the ability of older patients to think, learn, remember, make judgments, and carry out daily activities may help doctors plan treatment for older patients with cancer.
PURPOSE: This clinical trial is studying an assessment tool in older patients with cancer.
Official Title
Determining the Utility of an Assessment Tool for Older Patients With Cancer
Details
OBJECTIVES: Primary - Determine whether a geriatric assessment tool can predict toxicity to chemotherapy, defined as grade 3 or 4 toxicity, hospitalization, dose delay or reduction, or discontinuation of chemotherapy due to toxicity, in elderly patients with cancer. Secondary - Explore the longitudinal impact of cancer and chemotherapy treatment on geriatric assessment parameters. OUTLINE: Patients undergo assessments of functional status using the Timed Up and Go Assessment (measures physical mobility) and Karnofsky Physician-Rated Performance Rating Scale; and cognition using the Blessed Orientation-Memory-Concentration Test. These assessments are performed by healthcare personnel. Body mass index and the percentage of unintentional weight loss and the number of falls in the past 6 months are also assessed. Patients also complete the following self-administered questionnaires: Instrumental Activities of Daily Living (measures level of functioning and need for services); Activities of Daily Living (measures higher levels of physical functioning); Karnofsky Self-Reported Performance Rating Scale (related to survival and clinically significant illness); Physical Health Section of the Older American Resources and Services Questionnaire (measures comorbidity and the impact on daily activities); Hospital Anxiety and Depression Scale; Medical Outcomes Study (MOS) Social Activity Limitations Measure (measures the impact of cancer on patients' social functioning); and MOS Social Support Survey Emotional/Information and Tangible Subscales (measures perceived availability of social support). Patients then begin planned chemotherapy. After completion of chemotherapy (or a maximum of 12 months from study entry), patients undergo assessments and complete self-administered questionnaires as described above. PROJECTED ACCRUAL: A total of 750 patients will be accrued for this study.
Keywords
Cognitive/Functional Effects Psychosocial Effects of Cancer and Its Treatment Unspecified Adult Solid Tumor, Protocol Specific cognitive assessment psychosocial assessment and care Geriatric Assessment Tool
Eligibility
For people ages 65-120
DISEASE CHARACTERISTICS:
- Pathologically confirmed cancer
- Receiving chemotherapy for either adjuvant treatment or metastatic disease prior to beginning a new chemotherapy regimen
PATIENT CHARACTERISTICS:
- Must be able to understand English
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
- No prior enrollment in this trial
- No concurrent enrollment on a phase I clinical trial
Locations
- Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center
Orange California 92868 United States - Tower Cancer Research Foundation
Beverly Hills California 90211 United States - City of Hope Medical Center
Duarte California 91010-3000 United States
Details
- Status
- in progress, not accepting new patients
- Start Date
- Completion Date
- (estimated)
- Sponsor
- City of Hope Medical Center
- ID
- NCT00477958
- Study Type
- Interventional
- Participants
- Expecting 750 study participants
- Last Updated