Pulmonary Hemodynamics During Exercise - Research Network

a study on Pulmonary Circulation Diseases

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at UCLA
Dates
study started
completion around

Description

Summary

The purpose of this Clinical Research Collaboration is to investigate the prognostic implications of pulmonary hemodynamics during exercise based on a large scale multi-centre approach by using retrospective and prospective analysis of hemodynamic data.

Keywords

Pulmonary Circulation Diseases, assessment of pulmonary hemodynamics during exercise by right heart catheterization

Eligibility

You can join if…

Open to people ages 18 years and up

  • Patients (females and males; age: above 18yrs) with intermediate or high echocardiographic probability of PH and/or unexplained dyspnea, and/or associated conditions for PAH as clinical indication for RHC at rest and exercise
  • Written informed consent of participating subjects after being fully briefed (for prospective analysis)

You CAN'T join if...

  • Patients with incomplete hemodynamic data at rest or exercise
  • Patients without sufficient follow-up data (information on survival / lung transplantation)
  • advanced tumour disease or other diseases with a short life expectancy, except pulmonary vascular diseases
  • advanced heart failure with pulmonary arterial wedge pressure (PAWP) > 18 mmHg at rest
  • uncontrolled systemic arterial hypertension (RR values > 160/100 mmHg at rest)
  • FEV1<50% predicted
  • TLC<60% predicted

Locations

  • University of California, Los Angeles, Lung & Heart-Lung Transplant and Pulmonary Hypertension Programs, David Geffen School of Medicine accepting new patients
    Los Angeles California 90095 United States
  • Mayo Clinic, Division of Cardiovascular Diseases, Department of Medicine accepting new patients
    Rochester Minnesota 85259 United States

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Medical University of Graz
ID
NCT03954574
Study Type
Observational [Patient Registry]
Participants
Expecting 1500 study participants
Last Updated