for people ages 13-30 (full criteria)
Healthy Volunteers
healthy people welcome
study started
completion around
Principal Investigator
by Theodore B Moore, MD (ucla)



Pilot study enrolling obese post HSCT (hematopoietic stem cell transplantation) patients at the hematology/oncology clinic at the Mattel Children's Hospital, University of California, Los Angeles. Parameters include percent over the 95th percentile (%BMIp95), zBMI, fasting metabolic metrics, addictive eating habits, and motivation for change.


This is a pilot study enrolling obese patients, age 13-30, in an addiction model based smartphone mobile health (mHealth) weight loss intervention with coaching at a minimum of 100 days after hematopoietic stem cell transplantation. Patients will be screened and enrolled by the study coordinator, who will collect/submit biospecimens in addition to patient demographic characteristics and clinical outcomes. At the initial visit and enrollment, equipment will be disbursed to patients along with a schedule that outlines the 4-month intervention plan. After the initial visit, participants will participate in two additional in-clinic visits at 2 months and at the conclusion of the study at 4 months. Participants will also be involved in weekly phone calls and daily weekday texts to discuss their status for the 4 month duration.

This study will then correlate the results in change of BMI with patient characteristics, adherence to intervention, changes in metabolic parameters, physical activity levels, and addictive eating behaviors. Investigators are aiming to recruit a total of 20 adolescents/young adults total. No pilot group is necessary since the feasibility of this intervention has been validated in prior published studies.

The proposed model of delivery makes it possible to: 1) intervene with the participant and provide autonomy, 2) deliver the material over an extended period of time in a more convenient platform for the participant and families, 3) reduce many access barriers common in conventional outpatient obesity interventions, such as transportation or missed days of school and work, and 4) help youth develop skills to overcome their addictive eating behaviors.


Obesity, Stem Cell Transplant, Weight Loss, W8L2G mobile health (mHealth) app


You can join if…

Open to people ages 13-30

  • Patients ≥ 13 and ≤ 30 years old with a history of HSCT of any type, at least 100 days post-transplant at initial consultation of the study, will be eligible for the study.
  • Both male and female patients will be eligible.
  • Patients must classify as obese, represented as Body mass index [BMI] ≥85th percentile for age and gender.
  • Patients must also be able to read English since the app intervention is only available in English form.

You CAN'T join if...

  • Patients who are ≤ 13 or ≥ 30 years old are not eligible for the study.
  • Patients who are < 100 days post-transplant at initial consultation will not be eligible for the study, but may become eligible if they are >100 days post-transplant at their next consultation that falls within the enrollment window.
  • Patients whose BMI does not fall under the obese category will be excluded.
  • No patients will be excluded for any specific underlying medical condition, but decisions will be made on a case by case basis if a patient's functioning is deemed to significantly interfere with intervention participation.


  • UCLA Mattel Children's Hospital accepting new patients
    Los Angeles California 90095 United States

Lead Scientist at University of California Health

  • Theodore B Moore, MD (ucla)
    Professor of Clinical, Pediatrics, Medicine. Authored (or co-authored) 83 research publications


accepting new patients
Start Date
Completion Date
University of California, Los Angeles
Study Type
Expecting 20 study participants
Last Updated