for people ages 18 years and up (full criteria)
at UC Davis
study started
estimated completion



This study is testing a new brief mindfulness practice for people suffering from long COVID-19 symptoms. People suffering from long COVID are particularly vulnerable to negative emotions, as they must also cope with the long-term uncertainty of physical and psychological stress beyond the acute infection. The goal of the study is to measure the ability of a brief mindfulness practice to promote a sense of well-being in people suffering from long COVID.

Official Title

A Study of Positive Emotions With Long COVID (Post-Acute Sequelae of SARS CoV-2 Infection)


This is a pilot randomized waitlist-controlled clinical trial (RCT) testing a new brief self-care intervention for people suffering from post-acute sequelae SARS-CoV-2 infection (PASC). The overarching goal of this study is to establish the feasibility and early efficacy of microdosing mindfulness as a self-care intervention. The purpose of the intervention is to promote a sense of well-being among PASC patients who currently have limited access to other proven self-care modalities.

Our research question is whether our newly developed training can assist PASC patients to self-microdose mindfulness (5-15 seconds activities in everyday life) and improve on perceived metrics of well-being (primary outcome). Our hypothesis is that self-microdosing mindfulness will evoke positive emotions that can improve well-being on patients suffering of PASC-related symptoms beyond 3 months post COVID-19 infection. If effective, an increased frequency of the mindfulness activity will then help buffer negative emotions (e.g., anger, loneliness, etc.) experienced during the pandemic and associated with ongoing stress and/or somatic symptoms.


Post-Acute COVID-19 Syndrome, Mindfulness, COVID-19, Microdosing of mindfulness


You can join if…

Open to people ages 18 years and up

  • Able to participate in online zoom sessions and complete online surveys for 3 months
  • English speakers
  • Had a mild to moderate in severity COVID-19 infection > 3 months ago, feeling unwell, and are still experiencing in the present at least one PASC-related symptoms:
  • Coughing or feeling short of breath
  • Loss of smell or change in taste
  • Recurrent Fever
  • Body aches, headaches, chest pain, or stomach pain
  • Brain fog (feeling like you can't think clearly)
  • Having trouble sleeping
  • Feeling very tired
  • Mood changes

You CAN'T join if...

  • Adults that were admitted to an intensive care unit or placed on a respirator, had invasive heart (heart catheterization) or lung tests (bronchoscopy) performed, or were prescribed heart medications (e.g., inhalers, blood thinners, heart medications) to manage their condition.
  • Prisoners


  • University of California Davis accepting new patients
    Sacramento California 95817 United States


accepting new patients
Start Date
Completion Date
University of California, Davis
Study Type
Expecting 400 study participants
Last Updated