Sperm Preparation Prior to Intrauterine Insemination Study

a study on Infertility Reproductive Issues

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at UCSF
Dates
study started
completion around
Principal Investigator
by Mitchell Rosen, MD (ucsf)
Headshot of Mitchell Rosen
Mitchell Rosen

Description

Summary

This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.

Official Title

The Sperm Preparation Prior to Intrauterine Insemination Study (PIoUS)

Details

Study participants will be randomized to either standard sperm preparation (density gradient centrifugation) versus sperm preparation with the Zymot Multi sperm preparation device for their three month intrauterine insemination treatment course. Patients will follow standard treatment plans designed by their fertility physician and will be followed until referred for prenatal care at 8-10 weeks of pregnancy to determine pregnancy outcomes.

Keywords

Infertility, Infertility Secondary, Infertility Unexplained, Anovulation, Fertility Disorders, Reproductive Issues, Intrauterine Insemination, Insemination, Fertility, Zymot Multi sperm separation device, Density gradient centrifugation, Zymot sperm separation device

Eligibility

You can join if…

Open to people ages 18 years and up

  • Patients undergoing intrauterine insemination
  • Patient assigned female at birth with age <41

You CAN'T join if...

  • Any significant disease or psychiatric disorder that would interfere with the consenting process
  • Prior intrauterine insemination
  • Use of frozen donor sperm
  • Non-English speaker

Location

  • UCSF Center for Reproductive Health accepting new patients
    San Francisco California 94158 United States

Lead Scientist at University of California Health

  • Mitchell Rosen, MD (ucsf)
    Dr. Mitchell Rosen is a reproductive endocrinology and fertility expert at the UCSF Center for Reproductive Health. He also is director of the UCSF Fertillity Preservation Center, which helps patients with cancer preserve their ability to have children, despite aggressive cancer treatment.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT05693220
Study Type
Interventional
Participants
Expecting 270 study participants
Last Updated