Summary

Eligibility
for people ages 6-30 (full criteria)
Location
at UC Davis
Dates
study started
completion around
Principal Investigator
by Alexandra Duffy, DO (ucdavis)

Description

Summary

The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are:

  • Is brain development different in JoHD than Adult-onset Huntington's Disease (AoHD)?
  • Can reliable biomarkers for JoHD be found in brain structure and function?

Participants will be asked to complete cognitive tests, behavioral assessments, physical and neurologic evaluation, and MRI. Data collected will be compared to populations who are at-risk for HD and who have been diagnosed with HD as adults.

Official Title

Longitudinal Assessment of Brain Structure and Function in Juvenile Onset Huntington's Disease (JoHD)

Details

Keywords

Juvenile Huntington Disease, Juvenile-Onset Huntington Disease, JoHD, JHD, Juvenile Huntington's Disease, Huntington Disease

Eligibility

Locations

  • University of California Davis not yet accepting patients
    Sacramento California 95817 United States
  • University of Texas Health Science Center at Houston accepting new patients
    Houston Texas 77030 United States
  • University of Iowa Hospitals and Clinics, Department of Psychiatry accepting new patients
    Iowa City Iowa 52242 United States

Lead Scientist at University of California Health

  • Alexandra Duffy, DO (ucdavis)
    Associate Professor of Clinical, Med: Neurology, School of Medicine. Authored (or co-authored) 7 research publications

Details

Status
accepting new patients at some sites,
but this study is not currently recruiting here
Start Date
Completion Date
(estimated)
Sponsor
University of Iowa
Links
Study site Study site #2 Study site #3
ID
NCT05707663
Study Type
Observational
Participants
Expecting 40 study participants
Last Updated