Summary

Eligibility
for people ages 75 years and up (full criteria)
Location
at UCSD
Dates
study started
completion around
Principal Investigator
by Samir Gupta, MD MS (ucsd)

Description

Summary

Colorectal cancer is a leading cause of cancer death. Detection and removal of polyps can reduce risk for developing colorectal cancer. After finding and removing precancerous polyps, repeat colonoscopy is routinely recommended. However, it is unclear whether repeat additional colonoscopy further reduces risk for colorectal cancer. For older adults age 75 and older, the lack of this information is especially important, given that the risks of colonoscopy go up with age. This research will evaluate whether older adults with a prior history of precancerous polyps have higher colorectal cancer risks compared to older adults who had a prior normal colonoscopy, and whether, among those with prior precancerous polyps, repeating a colonoscopy after age 75 is associated with reduced cancer risk. The investigators will synthesize these data and gather perspectives from Veterans and clinical stakeholders to make recommendations on whether older adults with a prior history of polyps should continue or defer colonoscopy after age 75.

Details

Keywords

Colorectal Cancer, older adults, aging, Colorectal Neoplasms, adenoma vs no adenoma, colonoscopy vs no colonoscopy, Stakeholders

Eligibility

Locations

  • VA San Diego Healthcare System, San Diego, CA accepting new patients
    San Diego California 92161-0002 United States
  • VA Greater Los Angeles Healthcare System, West Los Angeles, CA accepting new patients
    West Los Angeles California 90073-1003 United States

Lead Scientist at University of California Health

  • Samir Gupta, MD MS (ucsd)
    Professor, Medicine, Vc-health Sciences-schools. Authored (or co-authored) 89 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
VA Office of Research and Development
ID
NCT05994482
Study Type
Observational
Participants
Expecting 130000 study participants
Last Updated