This study is in progress, not accepting new patients

Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia

a study on Aphasia, Acquired Aphasia Aphasia, Fluent Aphasia Non Fluent

Summary

Eligibility
for people ages 18-80 (full criteria)
Location
at UCSF
Dates
study started
completion around

Description

Summary

The goal of this clinical trial is to establish the feasibility and fidelity of a high-intensity exercise program for individuals with post-stroke aphasia. The main questions it aims to answer are:

  • Is it feasible for stroke survivors with aphasia to participate in a long in-person physical exercise program?
  • Does participation in a physical exercise program lead to physical fitness, cognitive, language and/or psychological changes?

Participants can take part in two different physical exercise interventions:

  • Low intensity intervention (control intervention);
  • High-intensity physical exercise intervention (target intervention).

Official Title

Exercising Language: Behavioral and Neurophysiological Changes After High-intensity Exercise Training in Post-stroke Aphasia

Keywords

Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia Non Fluent, physical exercise, high intensity interval training, cognition, physical fitness, balance, Wernicke Aphasia, Low-intensity physical exercise, High-intensity physical exercise

Eligibility

You can join if…

Open to people ages 18-80

  • aphasia following single or multiple ischemic or hemorrhagic stroke;
  • at least 6 months from the last stroke;
  • proficient in English before the stroke;
  • at least 8 years of education;
  • between the ages of 18 and 80;
  • independent with ambulation without a device (single-point cane accepted);
  • medically stable with no contraindications to participate in regular physical exercise as determined by the patient's own primary care provider or other treating provider.

You CAN'T join if...

  • prior history of dementia, neurologic illness (other than stroke), or substance abuse;
  • significant visual or hearing disabilities (e.g., neglect, uncorrected visual or hearing loss) that interfere with testing;
  • per self-report uncontrolled cardiorespiratory and/or metabolic disorders incompatible with exercise.

Locations

  • University of California San Francisco
    San Francisco California 94143 United States
  • University of San Francisco
    San Francisco California 94118 United States
  • University of California Berkeley
    Berkeley California 94720 United States
  • California State University East Bay
    Hayward California 94542 United States

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Berkeley
ID
NCT06185023
Study Type
Interventional
Participants
Expecting 12 study participants
Last Updated