Summary

Eligibility
for people ages 30-65 (full criteria)
Location
at UC Irvine
Dates
study started
completion around
Principal Investigator
by Hannah Lui Park, PhD (uci)
Headshot of Hannah Lui Park
Hannah Lui Park

Description

Summary

This is a pilot study to determine the feasibility of studying the Fasting-Mimicking Diet (FMD), a dietary approach that involves the consumption of a specifically formulated, calorie-restricted nutrition regimen with a customized macronutrient composition, ratio, and quantity over a 5- day period, on a larger scale in Asian Americans with prediabetes and to examine the preliminary effects of the diet in study participants.

The main questions the study aims to answer are:

  1. What are the recruitment, adherence, and attrition rates of eligible participants into the study?
  2. Does one FMD cycle result in changes in fasting blood glucose levels and physical measurements in study participants?

Participants will be asked to undergo one cycle of FMD (for 5 days), fill out surveys, and come in for a pre-FMD and post-FMD study visit, during which physical measurements and fasting blood glucose and ketone levels will be measured.

Official Title

Pilot Study on Fasting-Mimicking Diet in Asian Americans With Prediabetes

Keywords

Prediabetes, Prediabetic State, Glucose Intolerance, Fasting Mimicking Diet, Fasting Mimicking Diet (FMD)

Eligibility

You can join if…

Open to people ages 30-65

  • Identify as Asian American
  • Diagnosed with prediabetes according to at least one of the following:
  • HbA1C 5.7%-6.4%
  • Fasting blood glucose 100 to 125 mg/dL (5.6 to 6.9 mmol/L )
  • Oral glucose tolerance test (OGTT) 140-199 mg/dL at two hours

You CAN'T join if...

  • Individuals with a personal history of diabetes mellitus (ICD-10 codes E08-E13), cardiovascular disease, mental illness, drug dependency, pregnancy, and special dietary restrictions
  • Individuals taking insulin or insulin-like drugs and individuals taking hypoglycemic agents other than metformin
  • Individuals who are pregnant or breastfeeding
  • Individuals with anaphylaxis food allergies
  • Individuals who are allergic to tree nuts (macadamia, cashew, almond, pecan), soy, oats, sesame, or celery/celeriac
  • Individuals who have completed the FMD in the past year

Location

  • UC Irvine accepting new patients
    Irvine California 92617 United States

Lead Scientist at University of California Health

  • Hannah Lui Park, PhD (uci)
    Associate Professor In Residence, Pathology, School of Medicine. Authored (or co-authored) 49 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Irvine
ID
NCT06518798
Study Type
Interventional
Participants
Expecting 30 study participants
Last Updated