Summary

Eligibility
for people ages up to 17 years (full criteria)
Location
at UCSF
Dates
study started
completion around
Principal Investigator
by Emily Perito (ucsf)
Headshot of Emily Perito
Emily Perito

Description

Summary

This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer. Finding genetic markers among pediatric patients with acute recurrent pancreatitis and chronic pancreatitis may help identify patients who are at risk of pancreatic cancer.

Official Title

Pediatric Longitudinal Cohort Study of Chronic Pancreatitis (INSPPIRE 2)

Details

PRIMARY OBJECTIVE:

  1. To comprehensively characterize the pediatric population with acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) and determine predictors of early onset CP and its sequelae.

OUTLINE:

Patients complete quality-of-life (QoL) assessment and complete questionnaires for over 2 hours every 12 months for 4 years. Patients also undergo collection of blood and/or saliva (if blood samples are not available), urine, or stool at baseline or follow-up (if inadequate samples collected or missed at baseline).

After completion of the study, patients are followed up every 12 months.

Keywords

Chronic Pancreatitis, Exocrine Pancreas Carcinoma, Recurrent Acute Pancreatitis, Pancreatic Neoplasms, Pancreatitis, Biospecimen Collection, Quality-of-Life Assessment

Eligibility

Locations

  • UCSF Benioff Children's Hospital Oakland accepting new patients
    Oakland California 94609 United States
  • Cedars Sinai Medical Center accepting new patients
    Los Angeles California 90048 United States
  • Children's Hospital Los Angeles accepting new patients
    Los Angeles California 90027 United States
  • Stanford Cancer Institute Palo Alto accepting new patients
    Palo Alto California 94304 United States

Lead Scientist at University of California Health

  • Emily Perito (ucsf)
    Dr. Emily R. Perito is an professor at UCSF who specializes in pediatric liver and pancreatic disease, pediatric liver transplant, and pediatric gastroenterology. She is jointly appointed in the Departments of Pediatrics and of Epidemiology and Biostatistics and affiliated faculty with the Institute for Health Policy Studies.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
M.D. Anderson Cancer Center
ID
NCT06651580
Study Type
Observational
Participants
Expecting 1600 study participants
Last Updated