Summary

Eligibility
for females ages 18 years and up (full criteria)
Location
at UCSD
Dates
study started
completion around
Principal Investigator
by Barbara Parry, M.D. (ucsd)
Headshot of Barbara Parry
Barbara Parry

Description

Summary

The goal of this clinical trial is to learn more about mood, sleep, and activity during menopause. The main question it aims to answer is: can mood and sleep dysfunction in menopause be improved by resetting misaligned circadian rhythm through one night of strategic sleep timing adjustment and two weeks of exposure to bright light at a certain time of day? Researchers will compare sleep timing (earlier vs. later) and bright white light exposure (morning or evening) to investigate the effect of melatonin levels on mood, sleep, and activity. Participants will 1) submit urine samples to measure melatonin levels, 2) be assigned to advance or delay their sleep for one night, 3) sit in front of a light box for 30 minutes per day (morning or evening) for 14 days, 4) complete questionnaires about their mood and sleep, and 5) wear a device that will measure their activity.

Official Title

Chronobiological Basis of Depression During the Menopause Transition

Details

Keywords

Depression, Depression During the Menopausal Transition, Menopausal Depression, Menopause, sleep and light intervention, melatonin, circadian rhythm, Chronobiology, Depressive Disorder, Phase Advanced Intervention (PAI), Phase Delay Intervention (PDI)

Eligibility

Location

  • University of California San Diego Hillcrest Medical Center
    San Diego California 92103 United States

Lead Scientist at University of California Health

  • Barbara Parry, M.D. (ucsd)
    Biography Barbara L. Parry, M.D. is Professor of Psychiatry at the University of California, San Diego (UCSD) where she has served as Director of the Women’s Mood Disorders Clinic of the UCSD Outpatient Psychiatric Services, Director of the Women’s Mental Health Clinic at the San Diego Veterans Administration Healthcare Center and Associate Director of the Medical Student Clerkship in Psychiatry.

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Diego
ID
NCT06678880
Study Type
Interventional
Participants
Expecting 120 study participants
Last Updated