Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at UCSF
Dates
study started
study ends around
Principal Investigator
by Guo-Hao Lin, DDS, MS (ucsf)
Headshot of Guo-Hao Lin
Guo-Hao Lin

Description

Summary

This study is being done to see which of two common grafting techniques-mixing two different grafting materials or layering two grafting materials-works better to augment bone volume next to your dental implant(s). We want to know which technique results in better bone augmentation.

Official Title

Comparison of Dental Implant Placement With Simultaneous Sandwich Bone Augmentation vs. Mixed Bone Augmentation: a Randomized Controlled Pilot Study

Keywords

Peri-implant Bone and Soft Tissues, bone dehiscence, bone fenestration, dental implants, Sandwich bone augmentation, Mixed bone augmentation

Eligibility

You can join if…

Open to people ages 18 years and up

  • Minimum dentition of 20 permanent teeth
  • Single edentulous site at maxillary premolar, canine, lateral incisor, or central incisor
  • Adjacent teeth present with sufficient clearance for an implant crown
  • Ridge width between 4 mm and 7 mm at the edentulous site

You CAN'T join if...

  • Systemic criteria:
    • Current heavy smokers (>10 cigarettes per day) or heavy smokers who quitted less than 1 year
    • Pregnancy or lactating mothers
    • Diseases of the immune system or any medical condition that may influence the treatment outcome (for examples uncontrolled diabetes (HbA1c >7), uncontrolled cardiovascular disease, neurologic or psychiatric disorders, systemic infections, history of radiation therapy in the head and neck area, current use of oral bisphosphonates for >3 years or history of IV bisphosphonates use, current alcoholism or drug abuse, etc.)
  • Intraoral criteria:
    • Acute infection at/or adjacent to the edentulous site (e.g., sinus tract, swelling, etc.)
    • Observable gingival changes due to use of medications such as calcium antagonists, anticonvulsives, immunosuppressants, anti-inflammatory medications, etc.)
    • Generalized uncontrolled dental diseases, e.g. caries, periodontal diseases, etc.
    • Uncontrolled periodontal disease
    • Poor oral hygiene (>20% plaque score)
  • CBCT criteria:

    • More than 7 mm of alveolar ridge with at the edentulous site present on CBCT scans

  • Intraoperative criteria:
    • An implant without primary stability >35N

Location

  • Periodontology Clinic, UCSF School of Dentistry
    San Francisco California 94143 United States

Lead Scientist at University of California Health

  • Guo-Hao Lin, DDS, MS (ucsf)
    Dr. Guo-Hao (Alex) Lin is an Associate Professor of Clinical Orofacial Sciences and the Director of the Postgraduate Periodontics Residency Program. He joined UCSF Dental Center in 2017 and he provides patient care services limited to Periodontics & dental implants.

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT07832565
Study Type
Interventional
Participants
Expecting 30 study participants
Last Updated