Summary

for people ages 18-100 (full criteria)
healthy people welcome
at UCLA
study started
estimated completion:
V. Raman Muthusamy (ucla)

Description

Summary

A prospective outcomes study in patients with and esophageal cancer (EAC) and Barrett's esophagus (BE) associated neoplasia being evaluated for endoscopic eradication therapy (EET).

Official Title

A Multicenter Prospective Study Evaluating Outcomes of Endoscopic Eradication Therapy in Patients With Barrett's Esophagus Associated Neoplasia: The TREAT-BE (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus) Consortium

Details

Patients will be enrolled in this study at the participating centers when evaluated in gastro-intestinal (GI) clinics and endoscopy suites. Initial evaluation of patients will include collection of data on demographics, assessment of risk factors such as smoking, metabolic syndrome, family history and detailed medication history, and past surgical history. All patients will be complete questionnaires regarding Gastroesophageal Reflux Disease (GERD) symptoms, GERD related quality of life (QOL) and overall health related QOL. Details of all previous endoscopic and surgical evaluation along with histopathology data will be documented. Patients undergoing endoscopic evaluation at the participating centers will have their endoscopic and histopathology results documented. This will include data collection regarding use of advanced imaging techniques, details regarding tissue acquisition, EET and adverse events. Patients undergoing esophagectomy will have surgical details documented along with complications related to surgery. Similarly, details regarding chemoradiation treatments will be documented .

Keywords

Barrett's Esophagus Esophageal Cancer Esophageal Neoplasms Barrett Esophagus Endoscopic eradication therapies (EET) Esophagectomy Chemotherapy Radiation

Eligibility

You can join if…

Open to people ages 18-100

  • Patients with Barrett's related neoplasia and dysplasia. Patients with esophageal cancer

You CAN'T join if...

  • Patients with squamous cell carcinoma

Locations

  • UCLA Medical Center accepting new patients
    Los Angeles California 90095 United States
  • Washington University accepting new patients
    Saint Louis Missouri 63130 United States

Lead Scientist

  • V. Raman Muthusamy (ucla)
    Director, Interventional and General Endoscopy. Authored (or co-authored) 8 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of Colorado, Denver
ID
NCT02634645
Study Type
Observational
Last Updated