Summary

Eligibility
for people ages 18-64 (full criteria)
Healthy Volunteers
healthy people welcome
Location
at UCSF
Dates
study started
completion around
Principal Investigator
by Aric A Prather, PhD (ucsf)
Headshot of Aric A Prather
Aric A Prather

Description

Summary

This study will test the effect of race-based social rejection on polysomnography derived sleep outcomes and nocturnal cardiovascular psychophysiology in a sample of 80 African Americans and 80 Caucasian Americans. The investigators will test group differences on these outcomes as well as within subjects by testing impact of rejection compared to a non-rejection control night in the sleep laboratory.

Official Title

The Effects of Social Experiences on Sleep and Cardiovascular Functioning

Details

African Americans (AA) are disproportionally burdened by cardiovascular disease compared to Caucasian Americans (CA). Poor sleep, which is more common among AA, may serve as an important pathway in understanding these disparities. Race-based rejection has been cross-sectionally related to poor sleep and negative cardiovascular outcomes. To test the links between social experiences and sleep, participants will spend two nights in the sleep laboratory. One night will be a control night where participants complete low arousal tasks prior to bedtime. On a second night, the investigators will randomize 80 AA and 80 CA to either race-based social rejection (i.e., being rejected by an out-group member) or same-race social rejection prior to bedtime to test the causal influences of race-based rejection on objective sleep parameters, measured using polysomnography, and nocturnal cardiovascular functioning. The investigators will test group differences on these outcomes as well as within subjects by testing impact of rejection compared to a non-rejection control night in the sleep laboratory. The order of the control and rejection task night will be counterbalanced.

Keywords

Sleep, Blood Pressure, heart, stress, Social rejection

Eligibility

Location

  • University of California, San Francisco
    San Francisco California 94118 United States

Lead Scientist at University of California Health

  • Aric A Prather, PhD (ucsf)
    Aric Prather is a psychologist who treats insomnia with individual cognitive behavioral therapy. He also provides behavioral therapy to help patients adjust to using their continuous positive airway pressure (CPAP) equipment. Prather's research focuses on how poor sleep impacts physical health and emotional well-being.

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT03937973
Study Type
Interventional
Participants
About 139 people participating
Last Updated