Summary

Eligibility
for people ages 18-75 (full criteria)
Location
at UCSD
Dates
study started
completion around
Principal Investigator
by Pam R Taub, MD (ucsd)
Headshot of Pam R Taub
Pam R Taub

Description

Summary

The purpose of this study is to see if reducing the number of hours during which one eats each day will help reduce levels of LDL cholesterol and improve other markers of metabolic and cardiovascular health (i.e. blood sugar levels and blood pressure). The study also aims to assess changes in exercise capacity and trimethylamine N-oxide (TMAO) levels in response to Time Restricted Eating (TRE) and Intensive Cardiac Rehabilitation (ICR) versus ICR alone. TMAO is a metabolite, or a substance, produced during digestion and metabolism. Preliminary data illustrates a correlation between high levels of TMAO and higher risk of cardiovascular disease and mortality. We will also be looking at participants' long-term cardiovascular health status after they complete the ICR program.

Official Title

Impact of Time Restricted Eating on Exercise Capacity, Cardiometabolic Parameters, and Trimethylamine N-oxide (TMAO) Levels in Patients With Coronary Artery Disease (CAD) Undergoing Cardiac Rehabilitation

Keywords

Coronary Artery Disease, Time Restricted Eating, Circadian Rhythm, Cardiac Rehabilitation, Myocardial Ischemia, Coronary Disease, ICR (Intensive Cardiac Rehabilitation), ICR x TRE (Intensive Cardiac Rehabilitation x Time-Restricted Eating)

Eligibility

Location

  • Altman Clinical and Translational Research Institute
    La Jolla California 92093 United States

Lead Scientist at University of California Health

  • Pam R Taub, MD (ucsd)
    Pam R. Taub, MD, FACC, FASPC is Professor of Medicine at the UC San Diego School of Medicine in the Division of Cardiovascular Medicine. She is the Founding Director of the Step Family Foundation Cardiac Rehabilitation and Wellness Center. Dr. Taub was responsible for all aspects of creating the center.

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Diego
ID
NCT05014880
Study Type
Interventional
Participants
About 28 people participating
Last Updated