For people ages 18 years and up
Current Inclusion Criteria, as of 6/28/2024:
- Ischemic stroke within the prior 7 days.
- NIH Stroke Scale Score ≥1 at the time of enrollment
Previous Inclusion Criteria, prior to 6/28/2024:
- Ischemic stroke or TIA with ABCD ≥4, within prior 14 days.
Exclusion Criteria (for entire time period):
- pre-event inability to perform all of own basic ADLs
- unable to obtain informed consent from subject or legally authorized representative
- incarcerated
- known pregnancy
- current mechanical ventilation (can enroll later if this resolves) or tracheostomy
- current use of positive airway pressure, or use within one month prior to stroke
- anatomical or dermatologic anomaly that makes use of CPAP interface unfeasible
- severe bullous lung disease
- history of prior spontaneous pneumothorax or current pneumothorax
- hypotension requiring current treatment with pressors (can enroll later if this resolves)
- other specific medical circumstances that conceivably, in the opinion of the site PI, could render the patient at risk of harm from use of CPAP
- massive epistaxis or previous history of massive epistaxis
- cranial surgery or head trauma within the past 6 months, with known or possible CSF leak or pneumocephalus
- recent hemicraniectomy or suboccipital craniectomy (i.e. those whose bone has not yet been replaced), or any other recent bone removal procedure for relief of intracranial pressure
- current receipt of oxygen supplementation >4 liters per minute
- current contact, droplet, respiratory/airborne precautions
