Summary

Eligibility
for people ages 18-100 (full criteria)
Location
at UC Davis
Dates
study started
completion around
Principal Investigator
by Ryan M Martin (ucdavis)

Description

Summary

This study plans to evaluate the time course of inflammation in the brain after a moderate to severe traumatic brain injury using positron emission tomography (PET) brain imaging. Patients will undergo PET scans of the brain at two weeks and two months after injury to measure neuro-inflammation. The results of the PET scans will be analyzed and correlated with the risk of post-traumatic epilepsy.

Official Title

Imaging of Glial Activation and Risk for Post-Traumatic Epilepsy

Details

Keywords

Epilepsy, Post-Traumatic, neuroinflammation, activated microglia, TSPO, Traumatic Brain Injury, TBI, Positron emission tomography, Epilepsy, Post-Traumatic Epilepsy, [18F]DPA-714 Positron Emission Tomography Scan, Moderate to Severe Traumatic Brain Injury

Eligibility

Location

  • University of California, Davis accepting new patients
    Sacramento California 95817 United States

Lead Scientist at University of California Health

  • Ryan M Martin (ucdavis)
    Associate Professor, Med: Neurological Surgery, School of Medicine. Authored (or co-authored) 8 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Davis
ID
NCT03999164
Phase
Phase 1 Epilepsy Research Study
Study Type
Interventional
Participants
Expecting 30 study participants
Last Updated