Ischemic Stroke clinical trials at University of California Health
15 in progress, 9 open to eligible people
Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
open to eligible people ages 40 years and up
The purpose of this study is to evaluate whether milvexian compared to placebo reduce the risk of recurrent ischemic stroke.
at UC Davis UC Irvine UCLA
SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke
open to eligible people ages 18-110
SEACOAST 1 is a prospective, randomized, blinded endpoint trial comparing collateral vigor and clinical outcomes, with different forms of GA in patients with acute ischemic stroke due to anterior circulation large vessel occlusion (LVO) undergoing…
at UCLA
Sleep for Stroke Management and Recovery Trial
open to eligible people ages 18 years and up
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6…
at UC Davis UC Irvine UCLA UCSD UCSF
Strategy for Improving Stroke Treatment Response
open to eligible people ages 18 years and up
SISTER is a Phase-II, prospective, randomized, placebo-controlled, blinded, dose finding trial that aims to determine the safety and preliminary efficacy of TS23, a monoclonal antibody against the alpha-2 antiplasmin (a2-AP), in acute ischemic…
at UCSD
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
open to eligible people ages 18 years and up
The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke. The purpose of the study is to help doctors identify patients …
at UCLA UCSD
NOninVasive Intracranial PrEssure from Transcranial DoppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients
open to eligible people ages 18 years and up
This is an observational study in neurocritical care units at University of California San Francisco Medical Center (UCSFMC), Zuckerberg San Francisco General Hospital (ZSFGH), UC Davis, and Emory University. In this study, the investigators will…
at UC Davis UCSF
Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis
open to eligible people ages 30 years and up
An observational study to determine if individuals with increased platelet FcyRIIa will have a higher risk of ischemic events.
at UCLA
Stroke Recovery Initiative - Registry for Stroke Research Studies
open to eligible people ages 18 years and up
The Stroke Recovery Initiative is a nation-wide participant recruitment registry that connects people who have had a stroke with researchers who are working to develop new approaches to improve recovery after stroke.
at UCSF
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
open to eligible people ages 18 years and up
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, …
at UCLA UCSF
Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke
Sorry, in progress, not accepting new patients
Researchers are looking for a better way to prevent an ischemic stroke which occurs when a blood clot travelled to the brain in people who within the last 72 hours had: - an acute stroke due to a blood clot that formed outside the heart (acute…
at UC Irvine UCLA
BCI-FES Therapy for Stroke Rehabilitation
Sorry, in progress, not accepting new patients
There are over 7 million stroke survivors in the US alone, with approximately 795,000 new cases annually. Despite the best available physiotherapy, 30-60% of stroke survivors remain affected by difficulty walking, with foot weakness often being the…
at UC Irvine
Determinants of the Effectiveness of Robot-assisted Hand Movement Training
Sorry, in progress, not accepting new patients
The investigators would like to investigate the effectiveness of somatosensory training for robot-assisted hand motor rehabilitation after stroke.
at UC Irvine
Focal Cerebral Arteriopathy Steroid Trial
Sorry, accepting new patients by invitation only
This comparative effectiveness trial (CET) in children with suspected focal cerebral arteriopathy (FCA) presenting with arterial ischemic stroke (AIS) or transient ischemic attack (TIA) will compare the use of early corticosteroid treatment (Arm A)…
at UCSF
Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke
Sorry, not yet accepting patients
Many patients with acute ischemic stroke are ineligible for currently available standard treatments (clot-busting medication, also known as intravenous thrombolytic or mechanical removal of a clot), and many are non-responders, resulting in a low…
at UCLA UCSF
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
Sorry, not currently recruiting here
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability…
at UCLA
Our lead scientists for Ischemic Stroke research studies include Jason Hinman, MD, PhD Heather J Fullerton, MD, MAS David Reinkensmeyer, Ph.D Mersedeh Bahr Hosseini, MD Katherine Mun, MD Latisha K. Sharma, MD An Do David Liebeskind Radoslav Raychev, MD Jeffrey Saver, MD Royya Modir, MD Alon Avidan, MD, MPH Anthony S. Kim, MD, MAS.
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