Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at UCLA UCSF
Dates
study started
completion around
Principal Investigator
by Mersedeh Bahr Hosseini, MD (ucla)
Headshot of Mersedeh Bahr Hosseini
Mersedeh Bahr Hosseini

Description

Summary

Many patients with acute ischemic stroke are ineligible for currently available standard treatments (clot-busting medication, also known as intravenous thrombolytic or mechanical removal of a clot), and many are non-responders, resulting in a low rate of excellent outcomes, which necessitates the development of novel therapies.

In this study, investigators are testing a new treatment in which a weak electrical current will be applied via scalp electrodes to increase collateral blood flow to the brain and rescue the brain tissue at risk of injury. The primary aim is to find an optimal dose of this therapy that is both adequately safe and effective on imaging markers of brain tissue rescue.

Official Title

Transcranial Electrical Stimulation in Stroke EaRly After Onset Clinical Trial 2

Details

Keywords

Acute Ischemic Stroke, Cytoprotection, Collateral enhancement, Stroke, Ischemic Stroke, Ischemia, High-definition Cathodal Transcranial Direct Current Stimulation (HD C-tDCS)

Eligibility

Location

  • University of California- Los Angeles (UCLA)
    Los Angeles California 90095 United States

Lead Scientist at University of California Health

  • Mersedeh Bahr Hosseini, MD (ucla)
    Hs Associate Clinical Professor, Neurology, Medicine. Authored (or co-authored) 22 research publications

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Los Angeles
ID
NCT06440707
Phase
Phase 2 research study
Study Type
Interventional
Participants
Expecting 120 study participants
Last Updated