Summary

Eligibility
for people ages 14-18 (full criteria)
Location
at UCSF
Dates
study started
completion around
Principal Investigator
by Tony Yang (ucsf)

Description

Summary

The primary objective will be to study changes in putamen connectivity and depression severity in depressed teens with meditation training. H1: Putamen node strength will increase in the training group compared to the active controls. H2: This increase in node strength will correlate with practice amount recorded by participants. H3: There will be a significant reduction in self-rated depression symptoms following the training as measured by the Reynolds Adolescent Depression Scale (RADS-2), compared to controls. H4: This reduction will correlate with the increase in putamen node strength.

Design and Outcomes: The current research study design will utilize an individually randomized group treatment, open-label, active-controlled clinical trial to test the efficacy and safety of the investigator's innovative mindfulness meditation intervention (Training for Awareness Resilience and Action [TARA]) on the primary outcome (Putamen structural node strength) and secondary outcome (depression symptoms measured using Reynolds Adolescent Depression Scale [RADS-2]) in depressed adolescents between the ages of 14 to 18 years old.

Keywords

Depression Mild, Depression Moderate, Depression, Teen, Depression, Depressive Disorder, TARA, Psycho-Education

Eligibility

Location

  • UCSF accepting new patients
    San Francisco California 94143 United States

Lead Scientist at University of California Health

  • Tony Yang (ucsf)
    Professor, Psychiatry, School of Medicine. Authored (or co-authored) 98 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT05267340
Study Type
Interventional
Participants
Expecting 120 study participants
Last Updated