Summary

Eligibility
for people ages 12 years and up (full criteria)
Location
at UCSF
Dates
study started
study ends around

Description

Summary

The Gyrate Atrophy Ocular and Systemic Study characterizes the natural history of ornithine levels and retinal degeneration (RD) associated with disease-causing OAT variants in the presence of standard care dietary treatment regimens over 4 years. The research goal is to understand the impact of OAT mutations on plasma ornithine levels and retinal degeneration. Funding Source- FDA OOPD

Details

Keywords

Gyrate Atrophy, Gyrata of Choroid and Retina; Atrophy, Ornithine-δ-aminotransferase, OAT, Chorioretinal Degeneration, Atrophy

Eligibility

Locations

  • University of California San Francisco
    San Francisco California 94158 United States
  • University of Toronto, Hospital for Sick Children
    Toronto Ontario M5G0A4 Canada

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Jaeb Center for Health Research
Links
Foundation Fighting Blindness Public Website
ID
NCT05312736
Study Type
Observational
Participants
Expecting 45 study participants
Last Updated