Summary

Eligibility
for people ages 3-29 (full criteria)
Location
at UCSF
Dates
study started
completion around
Principal Investigator
by Alyssa T. Reddy (ucsf)

Description

Summary

Official Title

A Phase 2 Trial of Chemotherapy Followed by Response-Based Whole Ventricular &Amp; Spinal Canal Irradiation (WVSCI) for Patients With Localized Non-Germinomatous Central Nervous System Germ Cell Tumor

Details

Keywords

Central Nervous System Nongerminomatous Germ Cell Tumor, Choriocarcinoma, Embryonal Carcinoma, Immature Teratoma, Malignant Teratoma, Mixed Germ Cell Tumor, Pineal Region Germ Cell Tumor, Pineal Region Immature Teratoma, Pineal Region Yolk Sac Tumor, Suprasellar Germ Cell Tumor, Neoplasms, Germ Cell and Embryonal Neoplasms, Teratoma, Endodermal Sinus Tumor, Carboplatin, Etoposide, Etoposide phosphate, Ifosfamide, Isophosphamide mustard, Thiotepa, Podophyllotoxin, Lenograstim, Mesna, Biospecimen Collection, Filgrastim, Magnetic Resonance Imaging, Pegfilgrastim, Peripheral Blood Stem Cell Transplantation, Radiation Therapy, Second-Look Surgery, Plan A (chemotherapy, WVSCI, second-look surgery if needed), Plan B (chemotherapy, HDCSCR, second-look surgery if needed)

Eligibility

Locations

Lead Scientist at University of California Health

  • Alyssa T. Reddy (ucsf)
    Professor, Neurology, School of Medicine. Authored (or co-authored) 32 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Children's Oncology Group
ID
NCT04684368
Phase
Phase 2 research study
Study Type
Interventional
Participants
Expecting 160 study participants
Last Updated