Summary

Eligibility
for people ages 40-65 (full criteria)
Location
at UCLA
Dates
study started
completion around
Principal Investigator
by Rajesh Kumar, PHD (ucla)

Description

Summary

The majority of T2DM adults show thiamine (vitamin B1) deficiency which may contribute to impaired function. This study will examine patients with T2DM through brain MRI scans, cognition assessments, blood tests, and questionnaires. Our goal is to see if a thiamine treatment (taking vitamin B1 capsules) can improve function. Patients will be asked to come to UCLA two times three months apart and each visit will last about 2.5-3 hours.

Official Title

Type 2 Diabetes Mellitus and Blood Brain Barrier Improvement - A Randomized Clinical Trial

Details

Keywords

Type2diabetes, MRI, Thiamine Treatment, Thiamine Deficiency, Cognition Assessments, Diabetes Mellitus, Type 2 Diabetes Mellitus, Thiamine

Eligibility

Location

  • UCLA accepting new patients
    Los Angeles California 90095 United States

Lead Scientist at University of California Health

  • Rajesh Kumar, PHD (ucla)
    Professor-in-Residence, Anesthesiology, Medicine. Authored (or co-authored) 104 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Los Angeles
ID
NCT06322212
Phase
Phase 1 research study
Study Type
Interventional
Participants
Expecting 52 study participants
Last Updated