Summary

Eligibility
for people ages 22-75 (full criteria)
Location
at UCSF
Dates
study started
completion around
Principal Investigator
by Andrew Lee (ucsf)
Headshot of Andrew Lee
Andrew Lee

Description

Summary

This is a double-blinded, randomized, crossover study design for SEEG-guided 4-lead DBS for treatment-refractory OCD, followed by open label stimulation for an additional 6 months. The study will be conducted in 3 stages: Stage 1 will consist of SEEG brain mapping and optimization of stimulation parameters. Stage 2 will consist of 4-lead DBS surgery with bilateral IPGs and further optimization of stimulation parameters. Stage 3 will be randomized, crossover treatment, followed by open label treatment.

Official Title

A Double-Blinded, Randomized, Crossover Trial of Stereoencephalography- Guided Four-Lead Personalized Deep Brain Stimulation for Treatment-Refractory Obsessive Compulsive Disorder (SEEG-Guided DBS for OCD)

Details

Keywords

Obsessive-Compulsive Disorder, OCD, Compulsive Personality Disorder, Deep Brain Stimulation

Eligibility

Location

  • University of California, San Francisco accepting new patients
    San Francisco California 94143 United States

Lead Scientist at University of California Health

  • Andrew Lee (ucsf)
    Assistant Professor, Psychiatry, School of Medicine. Authored (or co-authored) 12 research publications. Research interests: OCD · Tic Disorder · Anxiety-Spectrum Disorders · Neuromodulation · Neural Circuits

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Andrew Moses Lee, MD, PhD
ID
NCT06347978
Study Type
Interventional
Participants
Expecting 10 study participants
Last Updated