Summary

Eligibility
for females ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
Location
at UC Irvine
Dates
study started
completion around

Description

Summary

Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women. The nuMoM2b Heart Health Study (nuMoM2b-HHS) has followed a demographically diverse cohort of women enrolled and richly phenotyped during their first pregnancy, with data and biospecimens prospectively collected for up to 7 years thereafter. The overarching scientific goal of this study is to define the relationship between adverse pregnancy outcomes (APOs) and CVD to optimize CVD prediction, prevention, and treatment strategies for women. Continued follow-up of this observational cohort, building on a foundation of existing high-quality data, biospecimens, and administrative structures with a robust framework for ancillary study development and implementation, provides a unique opportunity to address knowledge gaps regarding the early mechanisms and trajectory of CVD in women.

Details

Keywords

Cardiovascular Diseases, Adverse Pregnancy Outcomes, Stillbirth, Small for Gestational Age, Preterm Birth, Hypertensive Diseases of Pregnancy, Gestational Diabetes

Eligibility

Locations

  • University of California, Irvine Medical Center
    Orange California 92868 United States
  • Utah Valley Hospital
    Provo Utah 84604 United States

Details

Status
accepting new patients by invitation only
Start Date
Completion Date
(estimated)
Sponsor
RTI International
ID
NCT05472597
Study Type
Observational
Participants
Expecting 4048 study participants
Last Updated