Summary

Eligibility
for people ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
Location
at UC Davis UCLA UCSD
Dates
study started
completion around
Principal Investigator
by Zhaoping Li, MD (ucla)
Headshot of Zhaoping Li
Zhaoping Li

Description

Summary

Official Title

Nutrition for Precision Health, Powered by the All of Us Research Program

Details

The NPH study design includes three modules: Module 1, a study of participants' dietary intake; Module 2, a randomized crossover trial with three dietary interventions among participants in a community-dwelling setting; and Module 3, a similar trial to Module 2 except with participants in residence, all detailed in the following text. Briefly, Module 1 will observe participants for 8-10 days while consuming their usual diet. Modules 2 and 3 will include 3 dietary interventions, each administered for 14 days, followed by a washout period between each diet. The study will be conducted at multiple sites managed by 6 clinical centers throughout the United States.

An interdisciplinary team of clinical nutrition research experts will evaluate dietary assessment methods, microbial metagenomics and metatranscriptomics, targeted and untargeted metabolomics, computational and data science to advance our current understanding of nutrition which will inform personalized nutrition recommendations. The resulting artificial intelligence (AI) algorithms to predict individual responses to food will provide a foundation to create customized dietary approaches to optimize short- and long-term health.

Keywords

Nutrition, Health, Dietary Habits, Diet A, Diet B, Diet C, Liquid Mixed Meal Tolerance Test, Diet-Specific Mixed Meal Tolerance Test, Module 1, Module 2, Module 3

Eligibility

Locations

  • University of California, Los Angeles accepting new patients
    Los Angeles California 90024 United States
  • University of California, Davis accepting new patients
    Sacramento California 95817 United States
  • USDA Western Human Nutrition Research Center accepting new patients
    Davis California 95616 United States
  • Cedars Sinai Medical Center accepting new patients
    West Hollywood California 90069 United States

Lead Scientist at University of California Health

  • Zhaoping Li, MD (ucla)
    Zhaoping Li, M.D., Ph.D., holds the Lynda and Stewart Resnick Endowed Chair in Human Nutrition.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
RTI International
ID
NCT05701657
Study Type
Interventional
Participants
Expecting 8000 study participants
Last Updated