Lung Tumor clinical trials at UC Health

• 9-ING-41 in Patients With Advanced Cancers

  open to eligible people ages 18 years and up

  GSK-3β is a potentially important therapeutic target in human malignancies. The Actuate 1801 Phase 1/2 study is designed to evaluate the safety and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers.

  at UCSF

• COM701 in Subjects With Advanced Solid Tumors

  open to eligible people ages 18 years and up

  This is a Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary clinical activity of COM701 as monotherapy and in combination with a programmed cell death protein 1 (PD-1) inhibitor.

  at UCLA

• Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Patients With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors

  open to eligible people ages 18 years and up

  This is a Phase 1/2, open-label, first-in-human (FIH) study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary antineoplastic activity of pralsetinib (BLU-667) administered orally in patients with medullary thyroid cancer, RET-altered NSCLC and other RET-altered solid tumors.

  at UC Irvine

• The Watch the Spot Trial

  “Help us find the best timing for CT scans to keep an eye on small lung nodules.”

  Sorry, accepting new patients by invitation only

  This study will compare two clinically accepted protocols for surveillance imaging in individuals who are found to have a small pulmonary nodule on chest computed tomography (CT) scans.

  at UC Davis UCSF

Last updated: June 4, 2020