Dose-Escalation and Dose-Expansion of RMC-4630 and Cobimetinib in Relapsed/Refractory Solid Tumors
a study on Solid Tumor
Solid Tumor SHP2 PTPN11 NSCLC KRAS G12 BRAF Class 3 NF1 LOF KRAS amplification KRAS mutations advanced solid tumor advanced solid malignancies melanoma skin cancer ovarian cancer pancreatic cancer endometrium/uterus cancer bladder cancer cervical cancer carcinoma, non-small-cell lung neoplasm, squamous cell carcinoma, squamous cell esophageal neoplasms carcinoma, bronchogenic bronchial neoplasms lung neoplasms respiratory tract neoplasms thoracic neoplasms neoplasms by site neoplasms lung diseases respiratory tract diseases RMC-4630 Cobimetinib RMC-4630 and Cobimetinib
Lead Scientists at UC Health
- Sai-Hong Ignatius Ou, MD (uci)
Health Sciences Professor, Medicine. Authored (or co-authored) 5 research publications.
- Jonathan Riess, MD (ucdavis)
Assistant Professor, Hematology And Oncology. Authored (or co-authored) 56 research publications.
- Caroline McCoach, MD (ucsf)
Caroline McCoach is a thoracic oncologist who focuses on the treatment of patients with lung cancer as well as other thoracic malignancies. Her goal is to provide a personalized approach to treatment, based on each patient’s cancer type in combination with their individual treatment goals.
- accepting new patients
- Start Date
- Completion Date
- Revolution Medicines, Inc.
- Phase 1/2
- Study Type
- Last Updated